Rieden K, Adolph J, Mende U, Georgi P
Radiolgische Klinik, Universität Heidelberg.
Rontgenblatter. 1989 Feb;42(2):95-103.
The diagnostic relevance of the various radiological examination methods - skeleton scintigraphy, conventional x-ray film, computed tomography, sonography and magnetic resonance - was analysed on the basis of an examination of 4765 clinically or scintigraphically suspect skeleton segments in order to arrive at an effective but also economically justifiable diagnostic approach. Conventional skeleton scintigraphy should be employed as the first method of choice, since it has a sensitivity of 93% and is hence very suitable as a searching tool. To differentiate benign and malignant lesions it is absolutely imperative to conduct at the same time a x-ray control of any abnormal accumulation of nuclides, or of parts of the skeleton that display signs or symptoms. Conventional x-ray film diagnosis enabled correct diagnosis of the type of disease in 95% of the cases. In its capacity as a complementary examination method, computed tomography enabled correct diagnosis in 52% of the cases that had remained roentgenologically unclear. A pathological bone scintigram without any x-ray or CT correlate must be considered as being suspect of metastases if trauma is absent. Magnetic resonance proved to be the most sensitive method in identifying malignant infiltrations of the medullary space in two patients suffering from a clearly delineated pain syndrome with normal x-ray and CT findings. Sonography proved superior in detecting extraosseous tumour portions. The value of angiography is the preoperative vascular imaging of metastases of the possibility of performing therapeutic embolisation or intraarterial drug therapy.
基于对4765个临床或骨闪烁扫描怀疑有问题的骨骼部位的检查,分析了各种放射学检查方法——骨骼闪烁扫描、传统X线片、计算机断层扫描、超声检查和磁共振成像——的诊断相关性,以便得出一种既有效又在经济上合理的诊断方法。传统的骨骼闪烁扫描应作为首选的第一种方法,因为它的敏感度为93%,因此非常适合作为一种筛查工具。为了鉴别良性和恶性病变,绝对有必要同时对任何核素异常聚集部位或显示体征或症状的骨骼部位进行X线对照检查。传统X线片诊断在95%的病例中能够正确诊断疾病类型。计算机断层扫描作为一种补充检查方法,在52%的X线检查仍不清楚的病例中能够正确诊断。如果没有外伤,无任何X线或CT相关表现的病理性骨闪烁扫描必须被视为怀疑有转移。对于两名患有明确疼痛综合征且X线和CT检查结果正常的患者,磁共振成像被证明是识别骨髓腔恶性浸润最敏感的方法。超声检查在检测骨外肿瘤部分方面被证明更具优势。血管造影的价值在于术前对转移灶进行血管成像,以及进行治疗性栓塞或动脉内药物治疗的可能性。