Nolan Kaitlyn Wallace, Lucas Jordyn, Abbasian Javaneh
University of Illinois at Chicago, Chicago, Illinois.
University of Illinois at Rockford, Rockford, Illinois.
J AAPOS. 2015 Oct;19(5):445-9. doi: 10.1016/j.jaapos.2015.07.285.
To describe the use of irradiated cornea for scleral reinforcement in Ahmed glaucoma valve drainage implant (AGV) devices in children.
The medical records of patients <18 years of age who underwent AGV surgery with irradiated cornea as scleral reinforcement were reviewed retrospectively. The primary outcome measure was erosion of the drainage tube through the corneal patch graft. Secondary outcome measures included other major complications: persistent inflammation, wound dehiscence, transmission of infectious disease, endophthalmitis, and tube/plate self-explantation.
A total of 25 procedures (20 patients) met inclusion criteria. Average patient age was 70 months (range, 2 months to 17 years). Mean follow-up was 24.8 months (range, 6 months to 6.2 years). One tube experienced conjunctival exposure through two separate corneal grafts (2/25 cases [8%]), sequentially in the same eye. The first event occurred at month 3.5 after primary implantation of the tube shunt; the second erosion occurred following revision of the existing implant at month 1.5 postoperatively. There were 2 cases of auto-explantation, 2 cases of wound dehiscence, and 1 case of persistent inflammation. There were no cases of endophthalmitis or other infections.
To our knowledge, this is the first report describing the use of corneal patch grafts in children. Irradiated cornea improves cosmesis and enhances visualization of the tube. The risk of tube exposure was found to be low and comparable to other materials used as a patch graft.
描述在儿童艾哈迈德青光眼引流阀(AGV)装置中使用辐照角膜进行巩膜加固的情况。
回顾性分析年龄小于18岁且接受以辐照角膜作为巩膜加固的AGV手术患者的病历。主要观察指标是引流管通过角膜补片移植处的侵蚀情况。次要观察指标包括其他主要并发症:持续性炎症、伤口裂开、传染病传播、眼内炎以及引流管/引流盘自行脱出。
共有25例手术(20例患者)符合纳入标准。患者平均年龄为70个月(范围为2个月至17岁)。平均随访时间为24.8个月(范围为6个月至6.2年)。一根引流管在同一眼中先后通过两片不同的角膜移植片出现结膜暴露(2/25例[8%])。首次事件发生在引流管分流初次植入后3.5个月;第二次侵蚀发生在术后1.5个月对现有植入物进行翻修之后。有2例自行脱出、2例伤口裂开和1例持续性炎症。没有眼内炎或其他感染病例。
据我们所知,这是第一份描述在儿童中使用角膜补片移植的报告。辐照角膜改善了美观并增强了对引流管的可视性。发现引流管暴露的风险较低,与用作补片移植的其他材料相当。