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Boston 1 型角膜移植术后行巩膜扁平部房水引流植入物的效果。

Outcomes of pars plana glaucoma drainage implant in Boston type 1 keratoprosthesis surgery.

机构信息

Illinois Eye & Ear Infirmary, University of Illinois at Chicago School of Medicine, Chicago, IL.

出版信息

J Glaucoma. 2014 Jan;23(1):e39-44. doi: 10.1097/IJG.0b013e31829e55f8.

Abstract

PURPOSE

Glaucoma drainage implantation in conjunction with Boston Type 1 Keratoprosthesis placement is a surgical option in controlling postoperative glaucoma. The purpose of this study is to report outcomes of combined pars plana vitrectomy and glaucoma drainage implantation with corneal patch graft in Boston Type 1 Keratoprosthesis patients.

PATIENTS AND METHODS

A retrospective review of patients who underwent pars plana glaucoma drainage implantation in combination with Boston Type 1 Keratoprosthesis was performed. Preoperative and postoperative parameters collected and analyzed included: visual acuity, intraocular pressure, number of glaucoma medications to achieve intraocular pressure control, bandage contact lens fit, and postoperative complications.

RESULTS

Twenty eyes of 20 patients were identified; 95% had preoperative diagnosis of glaucoma, utilizing on an average 2.5 medications with an average intraocular pressure of 19.8 mm Hg (±6.3 mm Hg; range, 9 to 32.8 mm Hg). After placement of the pars plana glaucoma drainage implant, an average intraocular pressure of 19 mm Hg (±7.0 mm Hg; range, 8 to 30 mm Hg) by scleral pneumotonometry was achieved and 85% were deemed to have normal pressures by digital palpation. An average of 2.1 intraocular pressure-lowering medications were required on last follow-up. Average follow-up was 31.6 months (±17.4 mo; range, 12.3 to 71.6 mo). Two eyes required glaucoma drainage implant explantation: one eye due to endophthalmitis from a nonhealing corneal ulcer and the other eye due to corneal melt. None of our patients experienced conjunctival erosion over a pars plana positioned glaucoma drainage implant or tube.

CONCLUSIONS

For the long-term management of glaucoma in keratoprosthesis patients, a posteriorly placed pars plana glaucoma drainage implant with corneal patch graft in conjunction with keratoprosthesis has a low risk of erosion and postoperative complications.

摘要

目的

青光眼引流植入术联合波士顿 1 型角膜成形术是控制术后青光眼的一种手术选择。本研究旨在报告联合后房内玻璃体切割术和青光眼引流植入术联合角膜贴片移植治疗波士顿 1 型角膜成形术患者的结果。

方法

对接受后房内青光眼引流植入术联合波士顿 1 型角膜成形术的患者进行回顾性研究。收集和分析术前和术后的参数包括:视力、眼压、控制眼压所需的青光眼药物数量、绷带接触镜适配和术后并发症。

结果

共确定了 20 例 20 只眼的患者;95%的患者术前诊断为青光眼,平均使用 2.5 种药物,平均眼压为 19.8mmHg(±6.3mmHg;范围为 9 至 32.8mmHg)。在后房内青光眼引流植入术后,通过巩膜压平眼压计平均眼压为 19mmHg(±7.0mmHg;范围为 8 至 30mmHg),85%的患者通过数字触诊被认为眼压正常。最后一次随访时平均需要 2.1 种降眼压药物。平均随访时间为 31.6 个月(±17.4 个月;范围为 12.3 至 71.6 个月)。两例患者需要取出青光眼引流植入物:一例因未愈合的角膜溃疡引起眼内炎,另一例因角膜溶解。我们的患者中没有任何一例在放置在后房内的青光眼引流植入物或引流管处发生结膜侵蚀。

结论

对于角膜成形术患者的青光眼长期管理,后部放置的后房内青光眼引流植入术联合角膜贴片移植联合角膜成形术具有低侵蚀和术后并发症的风险。

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