Dixon Meredith G, Taylor Melanie M, Dee Jacob, Hakim Avi, Cantey Paul, Lim Travis, Bah Hawa, Camara Sékou Mohamed, Ndongmo Clement B, Togba Mory, Touré Leonie Yvonne, Bilivogui Pepe, Sylla Mohammed, Kinzer Michael, Coronado Fátima, Tongren Jon Eric, Swaminathan Mahesh, Mandigny Lise, Diallo Boubacar, Seyler Thomas, Rondy Marc, Rodier Guénaël, Perea William A, Dahl Benjamin
Emerg Infect Dis. 2015 Nov;21(11):2022-8. doi: 10.3201//eid2111.150684.
The largest recorded Ebola virus disease epidemic began in March 2014; as of July 2015, it continued in 3 principally affected countries: Guinea, Liberia, and Sierra Leone. Control efforts include contact tracing to expedite identification of the virus in suspect case-patients. We examined contact tracing activities during September 20-December 31, 2014, in 2 prefectures of Guinea using national and local data about case-patients and their contacts. Results show less than one third of case-patients (28.3% and 31.1%) were registered as contacts before case identification; approximately two thirds (61.1% and 67.7%) had no registered contacts. Time to isolation of suspected case-patients was not immediate (median 5 and 3 days for Kindia and Faranah, respectively), and secondary attack rates varied by relationships of persons who had contact with the source case-patient and the type of case-patient to which a contact was exposed. More complete contact tracing efforts are needed to augment control of this epidemic.
有记录以来最大规模的埃博拉病毒病疫情于2014年3月开始;截至2015年7月,疫情仍在3个主要受影响国家持续:几内亚、利比里亚和塞拉利昂。防控措施包括接触者追踪,以加快在疑似病例患者中发现病毒。我们利用关于病例患者及其接触者的国家和地方数据,对2014年9月20日至12月31日期间几内亚两个专区的接触者追踪活动进行了调查。结果显示,不到三分之一的病例患者(分别为28.3%和31.1%)在病例确诊前被登记为接触者;约三分之二(分别为61.1%和67.7%)没有登记接触者。疑似病例患者的隔离时间并非即时(金迪亚和法拉纳的中位数分别为5天和3天),二代发病率因与源病例患者接触者的关系以及接触者所接触的病例患者类型而异。需要更全面的接触者追踪工作来加强对此次疫情的控制。