肿瘤微环境与免疫治疗：整体优于局部。
Tumor Microenvironment and Immunotherapy: The Whole Picture Is Better Than a Glimpse.
机构信息
INSERM, UMRS1138, Laboratory of Integrative Cancer Immunology, Paris, 75006, France; Université Paris Descartes, Paris 75006, France; Cordeliers Research Centre, Université Pierre et Marie Curie Paris 6, Paris 75006, France.
INSERM, UMRS1138, Laboratory of Integrative Cancer Immunology, Paris, 75006, France; Université Paris Descartes, Paris 75006, France; Cordeliers Research Centre, Université Pierre et Marie Curie Paris 6, Paris 75006, France.
出版信息
Immunity. 2015 Oct 20;43(4):631-3. doi: 10.1016/j.immuni.2015.10.004.
Predicting cancer patients' response to therapy is essential for curing disease and improving quality of life. Garraway and colleagues demonstrate that the frequency and number of neoantigens, non-synonymous mutations, and adaptive immune genes, but not the assessment of individual recurrent neoantigens or mutations, predicts patient responses to immunotherapy.
预测癌症患者对治疗的反应对于治愈疾病和提高生活质量至关重要。Garraway 及其同事证明，新抗原、非同义突变和适应性免疫基因的频率和数量，但不是对个别复发性新抗原或突变的评估，可预测患者对免疫疗法的反应。
Zotero 插件