Megumi Koichi, Okumura Hiroshi, Shimonosono Masataka, Ijichi Tetsuya, Uchikado Yasuto, Omoto Itaru, Yo Hiroyoshi, Kita Yoshiaki, Uenosono Yoshikazu, Arigami Takaaki, Mori Shinichiro, Baba Kenji, Ishigami Sumiya, Owaki Tetsuhiro, Natsugoe Shoji
Dept. of Digestive Surgery, Breast and Thyroid Surgery.
Gan To Kagaku Ryoho. 2015 Oct;42(10):1307-9.
A 68-year-old woman was diagnosed with advanced esophageal cancer with lymph node metastasis, for which she received neoadjuvant chemoradiotherapy. During therapy, she had loss of appetite and weight; therefore, we inserted a nasal feeding tube for her nutrition, after which, she gained weight soon. After therapy, she had a high fever with lymphocytopenia and was diagnosed with cytomegalovirus infection because of significantly high CMV antigenemia. Ganciclovir was administered immediately, and she recovered soon. Two months later, we performed esophagectomy, and she recovered without complications. Immediate diagnosis of CMV infection, ganciclovir administration, and nutrition through a feeding tube were useful for the esophageal cancer patient in this report who had immunosuppression and malnutrition during chemoradiation.
一名68岁女性被诊断为晚期食管癌伴淋巴结转移，为此她接受了新辅助放化疗。治疗期间，她出现食欲不振和体重下降；因此，我们为她插入了鼻饲管以补充营养，之后她很快体重增加。治疗后，她出现高热伴淋巴细胞减少，由于巨细胞病毒（CMV）血症显著升高而被诊断为CMV感染。立即给予更昔洛韦治疗，她很快康复。两个月后，我们进行了食管切除术，她恢复良好，未出现并发症。对于本报告中在放化疗期间出现免疫抑制和营养不良的食管癌患者，CMV感染的及时诊断、更昔洛韦治疗以及通过饲管补充营养是有效的。
