Liu Chao, Sun Hui, Wang Wei-ting, Sun Jin-yue, Smith Mark A
Zhong Yao Cai. 2015 Mar;38(3):514-7.
To investigate the chemical constituents in the ethanol extract from the whole plant of Euphorbia lunulata.
The whole plant of Euphorbia lunulata was extracted by 95% ethanol, then partitioned by system solvents with different polarity. The ethyl acetate and n-butyl alcohol extracts were separated on silica gel, Sephadex LH-20,and MCI columns. The isolated compounds were determined by detailed analysis of their spectral data.
Twelve compounds were isolated and identified from the ethyl acetate and n-butyl alcohol extracts of Euphorbia lunulata and the structures were identified as 7β-methoxy-stigmast-5-ene-3β-ol (1), 7β-methoxy-stigmast-5-ene-3β,22β-diol(2), asperglaucide(3), moscatin (4), p-hydroxybenzoic acid (5),3-methoxy-4-hydroxy benzoic acid(6), erigeside C(7),5,7,4'-trihydroxy flavanone(8), kaempferol(9), quercetin(10), corosolic acid(11) and acacetin (12).
All compounds except for 9 and 10 are reported from this plant for the first time.
研究月腺大戟全草乙醇提取物中的化学成分。
月腺大戟全草用95%乙醇提取，然后用不同极性的系统溶剂进行萃取。乙酸乙酯提取物和正丁醇提取物通过硅胶柱、葡聚糖凝胶LH - 20柱和MCI柱进行分离。通过对分离得到的化合物的光谱数据进行详细分析来确定其结构。
从月腺大戟的乙酸乙酯提取物和正丁醇提取物中分离鉴定出12个化合物，其结构分别鉴定为7β - 甲氧基 - 豆甾 - 5 - 烯 - 3β - 醇（1）、7β - 甲氧基 - 豆甾 - 5 - 烯 - 3β，22β - 二醇（2）、曲霉蓝菌素（3）、莫斯卡亭（4）、对羟基苯甲酸（5）、3 - 甲氧基 - 4 - 羟基苯甲酸（6）、飞蓬苷C（7）、5，7，4'- 三羟基黄烷酮（8）、山柰酚（9）、槲皮素（10）、科罗索酸（11）和刺槐素（12）。
除化合物9和10外，其余化合物均为首次从该植物中报道。
