Ferretti Mark, Phillips John
Department of Urology, New York Medical College, Valhalla, New York USA.
Can J Urol. 2015 Oct;22 Suppl 1:60-6.
Prostatectomy for benign disease, also known as a 'simple prostatectomy', is neither simple in indication nor approach. In the post-Medical Therapy of Prostatic Symptoms (MTOPS), NCT00021814 trial era, the medical management of benign prostatic hyperplasia (BPH) and consequent bladder outlet obstruction (BOO) has shifted surgical intervention to those patients who are medical-non responders, present with advanced signs of BOO and obstructive uropathy, and those with prostate gland volumes beyond the size normally approachable with standard transurethral resection of the prostate (TURP). Simple prostatectomy through an open surgical approach is associated with improvements in BOO and lower urinary tract symptoms (LUTS) but at the expense of considerable surgical and perioperative morbidity. Advances in technology have made it possible for patients to be offered standard open surgical approaches as well as transurethral approaches with photon-based energy sources (i.e. laser prostatectomy) and laparoscopic simple prostatectomy. A review of the historical challenges of BPH and the standard-of-care of open prostatectomy will put into perspective the potential advantages and disadvantages of laparoscopic and robotic prostatectomy for the treatment of benign BOO due to BPH.
A careful review of the literature was performed utilizing PubMed and ClinicalKey searches to identify relevant articles. Search terms 'simple prostatectomy', 'robotic simple prostatectomy' and 'laparoscopic simple prostatectomy'.
Over 14 series of open simple prostatectomies and over 20 minimally invasive series were identified and used as a reference. Additionally, several review articles were identified and incorporated.
Simple prostatectomy may be performed safely in appropriately selected patients utilizing either open or minimally invasive approaches. Clinical criteria should be used to determine the appropriateness of either retropubic versus transvesical approach.
良性疾病前列腺切除术,也称为“单纯前列腺切除术”,其适应症和手术方式都并非简单。在前列腺症状医学治疗(MTOPS)试验(NCT00021814)后的时代,良性前列腺增生(BPH)及随之而来的膀胱出口梗阻(BOO)的药物治疗已将手术干预转向那些药物治疗无反应、出现BOO和梗阻性肾病晚期体征以及前列腺体积超过标准经尿道前列腺切除术(TURP)通常可处理大小的患者。通过开放手术方式进行的单纯前列腺切除术可改善BOO和下尿路症状(LUTS),但代价是相当大的手术及围手术期发病率。技术进步使患者能够选择标准开放手术方式以及基于光子能量源的经尿道手术方式(即激光前列腺切除术)和腹腔镜单纯前列腺切除术。回顾BPH的历史挑战及开放前列腺切除术的治疗标准,将有助于正确看待腹腔镜和机器人前列腺切除术治疗BPH所致良性BOO的潜在优缺点。
利用PubMed和ClinicalKey检索对文献进行仔细回顾,以识别相关文章。检索词为“单纯前列腺切除术”“机器人单纯前列腺切除术”和“腹腔镜单纯前列腺切除术”。
识别出14个以上开放单纯前列腺切除术系列和20多个微创系列并用作参考。此外,还识别并纳入了几篇综述文章。
对于适当选择的患者,采用开放或微创方法均可安全地进行单纯前列腺切除术。应使用临床标准来确定耻骨后与经膀胱入路的适用性。