Thaker Ashesh, Navadeh Soodabeh, Gonzales Hugo, Malekinejad Mohsen
Department of Radiology, University of California, San Francisco, San Francisco, California.
Global Health Sciences, University of California, San Francisco, San Francisco, California; Department of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran.
J Am Coll Radiol. 2015 Dec;12(12 Pt B):1434-45. doi: 10.1016/j.jacr.2015.06.033. Epub 2015 Oct 21.
The use of medical imaging has expanded greatly in the past three decades, raising concern about potential unwanted carcinogenic harms associated with exposure to ionizing radiation among patients. This study summarizes evidence of efficacy of interventions that have prompted policies, and structural-level interventions aimed at reducing radiation dose and risk of cancer, especially among women.
Using standard terms, we conducted searches in MEDLINE, Scopus, and Web of Science, and de-duplicated retrieved citations. We hand-searched the reference section of eligible studies and contacted radiology experts to identify studies missed from electronic searches. Two reviewers screened retrieved citations based on predefined eligibility criteria, to identify relevant studies, extract key information from each, rate the quality of evidence, and summarize data in tabular and graphical format.
From a total of 1,543 unique citations identified from all sources, 16 were included for data extraction. Half of the studies focused on reduction of ionizing exposure from CT, and half on x-ray or fluoroscopy. Identified interventions were broadly categorized as: policy or structural intervention (two; 13%); multipronged (four; 25%); dose-feedback system (five; 31%); provision of training (four; 25%); and quality-control audit (one; 6%). In general, multipronged programs had a higher range for dose reduction (22%-74%), followed by policy/structural interventions (37%-50%).
Existing evidence on the effectiveness of policies aimed at reducing patient radiation dose is disperse and low in quality. Compared with other approaches, multipronged efforts may offer more patient protection.
在过去三十年中,医学成像的应用大幅扩展,这引发了人们对患者接触电离辐射可能产生的潜在致癌危害的担忧。本研究总结了促使政策出台的干预措施以及旨在降低辐射剂量和癌症风险(尤其是女性)的结构层面干预措施的有效性证据。
我们使用标准术语在MEDLINE、Scopus和科学网中进行检索,并对检索到的文献进行去重。我们人工检索了符合条件的研究的参考文献部分,并联系放射学专家以识别电子检索遗漏的研究。两名评审员根据预先确定的纳入标准筛选检索到的文献,以识别相关研究,从每项研究中提取关键信息,评估证据质量,并以表格和图形形式汇总数据。
从所有来源共识别出1543篇独特的文献,其中16篇被纳入数据提取。一半的研究聚焦于降低CT的电离辐射暴露,另一半聚焦于X射线或荧光透视。识别出的干预措施大致分为:政策或结构干预(2项;13%);多管齐下(4项;25%);剂量反馈系统(5项;31%);提供培训(4项;25%);以及质量控制审核(1项;6%)。总体而言,多管齐下的方案在剂量降低方面的幅度更大(22% - 74%),其次是政策/结构干预(37% - 50%)。
关于旨在降低患者辐射剂量的政策有效性的现有证据分散且质量较低。与其他方法相比,多管齐下的努力可能为患者提供更多保护。