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经皮近端股薄肌肌腱切断术与开放手术一样有效和安全吗?

Is percutaneous proximal gracilis tenotomy as effective and safe as the open procedure?

作者信息

Hachache Bilal, Eid Tony, Ghosn Elias, Sebaaly Amer, Kharrat Khalil, Ghanem Ismat

机构信息

Department of Orthopaedic Surgery, Hôtel-Dieu de France Hospital, Saint-Joseph University, Alfred Naccache Street, Ashrafieh, Beirut, Lebanon.

出版信息

J Child Orthop. 2015 Dec;9(6):477-81. doi: 10.1007/s11832-015-0699-z. Epub 2015 Oct 26.

DOI:10.1007/s11832-015-0699-z
PMID:26499454
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4661155/
Abstract

PURPOSE

There is currently an increasing trend for percutaneous surgical interventions mainly in children with cerebral palsy (CP). The purpose of this study was to evaluate the effectiveness and safety of percutaneous proximal gracilis tenotomy (PPGT) in children with CP scheduled for hip adductor tenotomy.

METHODS

This is a prospective study of 59 hips in 31 consecutive patients with CP scheduled for hip adductor tenotomy in the setting of multilevel tenotomies or hip osteotomy (femoral or Dega). A pediatric orthopedic surgeon conducted a percutaneous adductor longus and gracilis tenotomy through the same stab wound. Another surgeon extended the wound to explore what had been cut during the PPGT, and completed the tenotomy if necessary (open proximal gracilis tenotomy; OPGT). Hip abduction with the hip and knee extended (HA) was assessed by a third surgeon (1) immediately before PPGT, i.e., directly after percutaneous adductor longus tenotomy (prePPGT), (2) after PPGT (postPPGT), and (3) following OPGT (postOPGT), using a goniometer, in a standardized reproducible manner. All three surgeons were blinded to each other's findings. Primary end-points included the percentage of muscle portion sectioned percutaneously and the improvement of HA angle. Comparison between HA before and after PPGT was performed using a paired t test with 95 % confidence interval (CI), and comparison between HA after PPGT and OPGT was performed using a Student's t-test with 95 % CI. The bleeding was assessed and other iatrogenic lesions were identified. The relationship between HA after PPGT and the percentage of muscle portion sectioned percutaneously was evaluated by calculating the Pearson correlation coefficient (p < 0.01).

RESULTS

Mean HA measured 33.71 degrees prePPGT and increased to 45.90 degrees postPPGT (p < 0.0001). The postOPGT HA averaged 48.71 degrees with no statistically significant gain compared with postPPGT (p = 0.21). The muscular portion of gracilis origin was cut to an average of 91.95 %; completely in only 14 hips, between 90 and 100 % in 35 hips, between 70 and 90 % in 9 hips, and between 60 and 70 % in 1 hip. The gain in HA did not correlate with the extent of the muscular portion sectioned percutaneously (R = -0.043). Minimal accidental section of adductor brevis postPPGT was encountered in 39 hips. Considerable bleeding postPPGT with hematoma formation requiring hemostasis during the open control procedure occurred in 30 hips. Partial iatrogenic injury of the anterior branch of the obturator nerve was encountered in one patient bilaterally with severe adductor contracture, due to an anatomic too medial variant.

CONCLUSIONS

This is the only prospective study concerning the outcome of PPGT. Although PPGT is fast, simple and effective, it is not as safe as the open procedure even when performed correctly by an experienced surgeon, mainly because of the increased risk of bleeding. The findings of the current study do not support its use as a 'standard-of-care' technique in children with hip adductor contracture.

LEVEL OF EVIDENCE

Level II therapeutic study-prospective comparative study.

摘要

目的

目前,经皮手术干预呈上升趋势,主要用于脑瘫(CP)患儿。本研究的目的是评估计划进行髋内收肌切断术的CP患儿经皮近端股薄肌切断术(PPGT)的有效性和安全性。

方法

这是一项对31例连续CP患儿的59个髋关节进行的前瞻性研究,这些患儿计划在多级切断术或髋截骨术(股骨或德加截骨术)的情况下进行髋内收肌切断术。一名小儿骨科医生通过同一个小切口进行经皮内收长肌和股薄肌切断术。另一名外科医生扩大切口,探查PPGT过程中切断的组织,必要时完成切断术(开放近端股薄肌切断术;OPGT)。由第三名外科医生使用量角器以标准化可重复的方式评估髋关节伸直、膝关节伸直时的髋关节外展(HA)情况:(1)在PPGT前即刻,即经皮内收长肌切断术后直接测量(术前PPGT);(2)PPGT后(术后PPGT);(3)OPGT后(术后OPGT)。所有三名外科医生对彼此的检查结果均不知情。主要终点包括经皮切断的肌肉部分的百分比以及HA角度的改善情况。使用95%置信区间(CI)的配对t检验对PPGT前后的HA进行比较,使用95%CI的学生t检验对PPGT后与OPGT后的HA进行比较。评估出血情况并识别其他医源性损伤。通过计算Pearson相关系数评估PPGT后HA与经皮切断的肌肉部分百分比之间的关系(p<0.01)。

结果

术前PPGT时平均HA为33.71度,术后PPGT时增加到45.90度(p<0.0001)。术后OPGT时HA平均为48.71度,与术后PPGT相比无统计学显著增加(p=0.21)。股薄肌起点肌肉部分平均切断91.95%;仅14个髋关节完全切断,35个髋关节切断90%至100%,9个髋关节切断70%至90%,1个髋关节切断60%至70%。HA的增加与经皮切断的肌肉部分范围无关(R=-0.043)。术后PPGT时39个髋关节出现内收短肌的最小意外切断。术后PPGT时有大量出血并形成血肿,在开放控制手术过程中需要止血的情况发生在30个髋关节。一名双侧严重内收肌挛缩的患者因解剖变异过于靠内侧,双侧出现闭孔神经前支部分医源性损伤。

结论

这是关于PPGT结果的唯一前瞻性研究。尽管PPGT快速、简单且有效,但即使由经验丰富的外科医生正确操作,它也不如开放手术安全,主要是因为出血风险增加。本研究结果不支持将其作为髋内收肌挛缩患儿的“标准治疗”技术。

证据水平

II级治疗性研究——前瞻性比较研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f492/4661155/a1133b7d9f32/11832_2015_699_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f492/4661155/d68dc564b5af/11832_2015_699_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f492/4661155/cd24b5d7f93b/11832_2015_699_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f492/4661155/38a19dca1495/11832_2015_699_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f492/4661155/a1133b7d9f32/11832_2015_699_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f492/4661155/d68dc564b5af/11832_2015_699_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f492/4661155/cd24b5d7f93b/11832_2015_699_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f492/4661155/38a19dca1495/11832_2015_699_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f492/4661155/a1133b7d9f32/11832_2015_699_Fig4_HTML.jpg

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