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牙科汞合金模型中的蒙特卡罗剂量计算。

Monte Carlo dose calculation in dental amalgam phantom.

作者信息

Aziz Mohd Zahri Abdul, Yusoff A L, Osman N D, Abdullah R, Rabaie N A, Salikin M S

机构信息

Oncological and Radiological Science Cluster, Advance Medical and Dental Institute, Universiti Sains Malaysia, Kepala Batas 13200, Penang, Malaysia.

Department of Nuclear Medicine, Radiotherapy, and Oncology, School of Medical Science, Universiti Sains Malaysia, Penang, Malaysia.

出版信息

J Med Phys. 2015 Jul-Sep;40(3):150-5. doi: 10.4103/0971-6203.165080.

Abstract

It has become a great challenge in the modern radiation treatment to ensure the accuracy of treatment delivery in electron beam therapy. Tissue inhomogeneity has become one of the factors for accurate dose calculation, and this requires complex algorithm calculation like Monte Carlo (MC). On the other hand, computed tomography (CT) images used in treatment planning system need to be trustful as they are the input in radiotherapy treatment. However, with the presence of metal amalgam in treatment volume, the CT images input showed prominent streak artefact, thus, contributed sources of error. Hence, metal amalgam phantom often creates streak artifacts, which cause an error in the dose calculation. Thus, a streak artifact reduction technique was applied to correct the images, and as a result, better images were observed in terms of structure delineation and density assigning. Furthermore, the amalgam density data were corrected to provide amalgam voxel with accurate density value. As for the errors of dose uncertainties due to metal amalgam, they were reduced from 46% to as low as 2% at d80 (depth of the 80% dose beyond Zmax) using the presented strategies. Considering the number of vital and radiosensitive organs in the head and the neck regions, this correction strategy is suggested in reducing calculation uncertainties through MC calculation.

摘要

在现代放射治疗中,确保电子束治疗中治疗剂量传递的准确性已成为一项巨大挑战。组织不均匀性已成为精确剂量计算的因素之一,这需要像蒙特卡罗(MC)这样的复杂算法计算。另一方面,治疗计划系统中使用的计算机断层扫描(CT)图像作为放射治疗的输入需要可靠。然而,当治疗区域存在金属汞合金时,输入的CT图像会出现明显的条纹伪影,从而导致误差来源。因此,金属汞合金体模经常会产生条纹伪影,这会导致剂量计算出现误差。于是,应用了一种条纹伪影减少技术来校正图像,结果在结构描绘和密度赋值方面观察到了更好的图像。此外,对汞合金密度数据进行了校正,以给汞合金体素提供准确的密度值。至于由于金属汞合金导致的剂量不确定性误差,使用所提出的策略,在d80(超过Zmax的80%剂量深度)处,它们从46%降低到了低至2%。考虑到头颈部区域重要和放射敏感器官的数量,建议采用这种校正策略通过MC计算来减少计算不确定性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59cf/4594384/b4fdbff44ebf/JMP-40-150-g001.jpg

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