Hasegawa Urara, Tateishi Naoya, Uyama Hiroshi, van der Vlies André J
Frontier Research Base for Young Researchers and Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Macromol Biosci. 2015 Nov;15(11):1626. doi: 10.1002/mabi.201570042.
Back Cover: The micellar prodrugs of desmethyl anethole dithiolethione (ADT-OH) with different hydrolysis rates prepared from block copolymers having ADT-OH linked via an ester bond using glycine and isoleucine linkers are presented. Micelles having a glycine linker inhibit proliferation of cancer cells. Further details can be found in the article by U. Hasegawa, N. Tateishi, H. Uyama, A. J. van der Vlies on page 1512.
展示了由具有通过酯键连接的去甲基茴芹二硫醇硫酮（ADT-OH）的嵌段共聚物，使用甘氨酸和异亮氨酸连接体制备的具有不同水解速率的胶束前药。具有甘氨酸连接体的胶束可抑制癌细胞的增殖。更多细节可在U. Hasegawa、N. Tateishi、H. Uyama、A. J. van der Vlies发表于第1512页的文章中找到。
