儿童普卢默-文森综合征
Plummer-Vinson Syndrome in Children.
作者信息
Butori Mathilde, Mahmoudi Sana, Dugelay-Ecochard Emmanuelle, Belarbi Nadia, Bellaïche Marc, Hugot Jean-Pierre, Viala Jérôme
机构信息
*Departments of Pediatric Digestive and Respiratory Diseases †Radiology, Robert-Debré Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
出版信息
J Pediatr Gastroenterol Nutr. 2015 Nov;61(5):547-52. doi: 10.1097/MPG.0000000000000842.
OBJECTIVES
Plummer-Vinson syndrome (PVS), also called Kelly-Paterson syndrome, is a rare cause of dysphagia in children. This syndrome associates single or multiple webs in the upper esophagus with frequent iron deficiency.
METHODS
We reported 3 pediatric cases of PVS before analyzing all of the cases of PVS in children reported in the PubMed and EMBASE databases.
RESULTS
Among 17 reported PVS cases in children, all of the patients experienced iron-deficiency anemia, and no immunological disease was reported. The male/female ratio was 1/1.9, and most cases were observed in adolescents. Conversely to adults, endoscopic dilation was often necessary because dysphagia resisted iron supplementation. A single dilation was usually sufficient. One case of pediatric PVS experienced esophageal cancer in adulthood.
CONCLUSIONS
In the case of dysphagia in children, a swallow barium exploration with lateral incidence should look for PVS. Conversely to adults, an endoscopic dilation is frequently necessary to control dysphagia in children.
目的
普卢默-文森综合征（PVS），也称为凯利-帕特森综合征，是儿童吞咽困难的罕见病因。该综合征表现为食管上段有单个或多个蹼，并常伴有缺铁。
方法
在分析PubMed和EMBASE数据库中报告的所有儿童PVS病例之前，我们报告了3例儿童PVS病例。
结果
在报告的17例儿童PVS病例中，所有患者均患有缺铁性贫血，未报告有免疫性疾病。男女比例为1/1.9，大多数病例见于青少年。与成人相反，由于吞咽困难对补铁治疗无效，内镜扩张术常常是必要的。单次扩张通常就足够了。1例儿童PVS患者成年后患食管癌。
结论
对于儿童吞咽困难病例，应进行侧位吞钡造影检查以寻找PVS。与成人相反，内镜扩张术常常是控制儿童吞咽困难所必需的。
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