Lockyer Megan G, Rosen Daniel G
Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, U.S.A.
Anticancer Res. 2015 Nov;35(11):6171-4.
Extraskeletal myxoid chondrosarcoma is a rare tumor with an indolent course, high propensity for local recurrence, metastases, and propensity for the proximal extremities of middle-aged males.
We present the case of a 44-year-old man with an extraskeletal myxoid chondrosarcoma in the plantar fascia of the medial arch initially thought to be a plantar fibroma. Magnetic resonance imaging of the lesion demonstrated a lobulated subcutaneous mass plantar to the tarsal bones and inseparable from the fascia. Microscopic examination revealed a lobulated lesion composed of cords and nests of round to spindled malignant cells in a blue-gray myxoid matrix surrounded by fibrous septae. The malignant cells displayed variable positivity for S-100.
Plantar extraskeletal myxoid chondrosarcoma is a rare occurrence. It should always be considered in the differential diagnosis of masses arising in the plantar fascia of the foot.
骨外黏液样软骨肉瘤是一种罕见肿瘤,病程进展缓慢,局部复发及转移倾向高,好发于中年男性的四肢近端。
我们报告一例44岁男性患者,其足底内侧弓跖腱膜处患有骨外黏液样软骨肉瘤,最初被误诊为跖纤维瘤。该病变的磁共振成像显示为位于跗骨下方的分叶状皮下肿块,与筋膜相连。显微镜检查显示,病变呈分叶状,由圆形至梭形恶性细胞条索和巢状结构组成,位于蓝灰色黏液样基质中,周围有纤维间隔。恶性细胞S-100呈不同程度阳性。
足底骨外黏液样软骨肉瘤罕见。在足部跖腱膜肿物的鉴别诊断中应始终考虑到该病。