Iorio Natalya, Bernstein Gregory R, Malik Zubair, Schey Ron
Department of Medicine, Section of Gastroenterology, Temple University Hospital, Philadelphia, PA.
ACG Case Rep J. 2015 Oct 9;3(1):17-9. doi: 10.14309/crj.2015.87. eCollection 2015 Oct.
A 63-year-old woman with abdominal pain and melena developed a palpable, purpuric rash and acute kidney injury. Skin and kidney biopsy confirmed Henoch-Schönlein purpura. Upper endoscopy revealed diffuse, circumferential, black-appearing mucosa of the esophagus consistent with acute esophageal necrosis (AEN), also known as black esophagus. AEN is a very rare cause of gastrointestinal hemorrhage with a high mortality risk. To our knowledge, there have been no prior reports of AEN associated with Henoch-Schonlein purpura or other vasculitis.
一名63岁腹痛伴黑便的女性出现可触及的紫癜性皮疹及急性肾损伤。皮肤及肾脏活检确诊为过敏性紫癜。上消化道内镜检查显示食管黏膜弥漫性、环形发黑,符合急性食管坏死(AEN),也称为黑色食管。AEN是胃肠道出血的一种非常罕见的病因,具有很高的死亡风险。据我们所知,此前尚无AEN与过敏性紫癜或其他血管炎相关的报道。