Novák J
Békés Megyei Képviselötestület Pándy Kálmán Kórháza III. Belgyógyászat-Gastroenterológia, Gyula.
Orv Hetil. 1997 Aug 31;138(35):2169-73.
During a 10 years period 62 adult patients were admitted with diagnosis of Schönlein-Henoch purpura in our hospital. 25 female and 37 male patients ranged from 30 to 87 years (mean: 59.5 years) presenting with cutan, joint, renal and particularly abdominal involvement were investigated retrospectively. During the course of the disease, all patients developed purpuric rash (100%), 14 (22.5%) patients had joint symptoms and renal involvement occurred in 12 (19.3%) patients. In this study, we discuss 15 (24%) patients with gastrointestinal symptoms appearing in Henoch's purpura. Analysis of the gastrointestinal clinical features revealed: abdominal pain 13 (86%), massive colorectal bleeding 3 (20%), occult blood loss 10 (66%) vomiting 6 (40%) and diarrhoea in 3 (20%) patients. All the patients underwent lower and upper endoscopic examination, in 3 cases the author saw purpuric mucosal lesions in duodenum and in 8 patients were also found coin-like elevated lesions, additionally, biopsy from colonic lesions showed leukocytoclastic vasculitis. It is concluded that endoscopy can be helpful in the diagnosis and treatment of Schönlein-Henoch purpura, especially is those without typical skin rash.
在10年期间，我院收治了62例诊断为过敏性紫癜的成年患者。回顾性研究了25例女性和37例男性患者，年龄在30至87岁之间（平均59.5岁），这些患者表现为皮肤、关节、肾脏尤其是腹部受累。在疾病过程中，所有患者均出现紫癜疹（100%），14例（22.5%）患者有关节症状，12例（19.3%）患者出现肾脏受累。在本研究中，我们讨论了15例（24%）出现胃肠道症状的过敏性紫癜患者。胃肠道临床特征分析显示：腹痛13例（86%）、大量结肠出血3例（20%）、潜血10例（66%）、呕吐6例（40%）、腹泻3例（20%）。所有患者均接受了上下内镜检查，作者在3例患者的十二指肠中看到紫癜性黏膜病变，8例患者还发现了硬币样隆起病变，此外，结肠病变活检显示白细胞破碎性血管炎。结论是内镜检查有助于过敏性紫癜的诊断和治疗，尤其是对于那些没有典型皮疹的患者。
