Sunnetcioglu Aysel, Ekin Selami, Bayram Irfan, Ekinci Omer, Bugday Inci Bahadır
Department of Chest Diseases, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey.
Department of Pathology, Yuzuncu Yil, Faculty of Medicine, Van, Turkey.
Clin Respir J. 2017 Nov;11(6):1057-1059. doi: 10.1111/crj.12408. Epub 2015 Nov 18.
Endobronchial plasmacytoma is a rare manifestation of extramedullary plasmacytoma. A 49-year-old woman with a history of multiple myeloma consulted to our pulmonary service with progressive dyspnoea and cough and abnormal chest X-ray. A lesion measuring 6 × 5 cm in size existed in anterior baseline of the right lung's lower lobe in thoracic computed tomography in addition to right bronchial narrowing and atelectasis distal in lesions. Diagnostic bronchoscopy was performed previously for the obstruction and biopsy was taken from the lesion in the right middle lobe bronchus. Endobronchial biopsies showed extensive tumour infiltration with plasmocytoid cells. Immunohistochemistry was positive CD138 and Lamda. Microscopic and immunohistochemical findings supported the diagnosis of extramedullary endobronchial plasmacytoma.
支气管内浆细胞瘤是髓外浆细胞瘤的一种罕见表现。一名有多发性骨髓瘤病史的49岁女性因进行性呼吸困难、咳嗽及胸部X线异常前来我院呼吸科就诊。胸部计算机断层扫描显示右肺下叶前基底段有一个大小为6×5 cm的病变,此外病变远端右支气管狭窄及肺不张。此前因阻塞行诊断性支气管镜检查,并从右中叶支气管病变处取材活检。支气管内活检显示浆细胞样细胞广泛浸润肿瘤。免疫组化CD138和λ呈阳性。显微镜及免疫组化结果支持髓外支气管内浆细胞瘤的诊断。