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支气管内髓外浆细胞瘤。1例报告。

Endobronchial extramedullary plasmacytoma. Report of one case.

作者信息

Terzi A, Furlan G, Zannoni M, Adovasio A, Gorla A

机构信息

Divisione di Chirurgia Toracica, Ospedale Civile Maggiore Azienda Ospedaliera Verona, Italy.

出版信息

Lung Cancer. 1996 Dec;16(1):95-100. doi: 10.1016/s0169-5002(96)00616-2.

DOI:10.1016/s0169-5002(96)00616-2
PMID:9017589
Abstract

A patient underwent a subtotal resection of the tracheobronchial carina for an obstructing endobronchial lesion. Preoperative biopsies of the lesion were not diagnostic. After resection, the histological examination of the specimen removed demonstrated an extramedullary plasmacytoma infiltrating the bronchial wall. Immunohistochemical studies showed monoclonality for kappa light chains. The postoperative course was uneventful and the screening for multiple myeloma was negative. No adjuvant treatment was given and the patient is currently alive and free of disease 63 months after the resection. Primary endobronchial plasmacytoma is a very rare disease: it is unclear which is the best treatment for endobronchial plasmacytoma. However, complete surgical resection has allowed a long-term survival, free of disease.

摘要

一名患者因支气管内阻塞性病变接受了气管支气管隆突次全切除术。术前病变活检未能明确诊断。切除术后,对切除标本的组织学检查显示为髓外浆细胞瘤浸润支气管壁。免疫组化研究显示κ轻链呈单克隆性。术后过程顺利,多发性骨髓瘤筛查为阴性。未给予辅助治疗,患者目前在切除术后63个月仍存活且无疾病。原发性支气管内浆细胞瘤是一种非常罕见的疾病:目前尚不清楚支气管内浆细胞瘤的最佳治疗方法是什么。然而,完整的手术切除已实现了长期无病生存。

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Endobronchial extramedullary plasmacytoma. Report of one case.支气管内髓外浆细胞瘤。1例报告。
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引用本文的文献

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Solitary endobronchial plasmacytoma-a rare differential of an endobronchial mass.孤立性支气管内浆细胞瘤——一种罕见的支气管内肿物鉴别诊断。
Indian J Thorac Cardiovasc Surg. 2023 Nov;39(6):629-631. doi: 10.1007/s12055-023-01557-w. Epub 2023 Jul 21.
2
A rare case of primary solitary endobronchial plasmacytoma.原发性孤立性支气管内浆细胞瘤 1 例罕见报告
Thorac Cancer. 2021 Mar;12(6):958-961. doi: 10.1111/1759-7714.13853. Epub 2021 Jan 27.
3
Primary endobronchial plasmacytoma involving local lymph nodes and presenting with rare immunoglobulin G lambda monoclonal gammopathy.
原发性支气管内浆细胞瘤累及局部淋巴结,并伴有罕见的免疫球蛋白 G 入型单克隆丙种球蛋白血症。
Can Respir J. 2012 May-Jun;19(3):e28-30. doi: 10.1155/2012/968254.