Terzi A, Furlan G, Zannoni M, Adovasio A, Gorla A
Divisione di Chirurgia Toracica, Ospedale Civile Maggiore Azienda Ospedaliera Verona, Italy.
Lung Cancer. 1996 Dec;16(1):95-100. doi: 10.1016/s0169-5002(96)00616-2.
A patient underwent a subtotal resection of the tracheobronchial carina for an obstructing endobronchial lesion. Preoperative biopsies of the lesion were not diagnostic. After resection, the histological examination of the specimen removed demonstrated an extramedullary plasmacytoma infiltrating the bronchial wall. Immunohistochemical studies showed monoclonality for kappa light chains. The postoperative course was uneventful and the screening for multiple myeloma was negative. No adjuvant treatment was given and the patient is currently alive and free of disease 63 months after the resection. Primary endobronchial plasmacytoma is a very rare disease: it is unclear which is the best treatment for endobronchial plasmacytoma. However, complete surgical resection has allowed a long-term survival, free of disease.
一名患者因支气管内阻塞性病变接受了气管支气管隆突次全切除术。术前病变活检未能明确诊断。切除术后,对切除标本的组织学检查显示为髓外浆细胞瘤浸润支气管壁。免疫组化研究显示κ轻链呈单克隆性。术后过程顺利,多发性骨髓瘤筛查为阴性。未给予辅助治疗,患者目前在切除术后63个月仍存活且无疾病。原发性支气管内浆细胞瘤是一种非常罕见的疾病:目前尚不清楚支气管内浆细胞瘤的最佳治疗方法是什么。然而,完整的手术切除已实现了长期无病生存。