Thorne M C
Phys Med Biol. 1977 Jan;22(1):36-46. doi: 10.1088/0031-9155/22/1/005.
The dosimetry of alpha-emitting radionuclides in bone is discussed. Results are presented for average dose rates to tissues close to endosteal surfaces and to haematopoietic bone marrow from thin plane sources of radionuclides buried to different depths in bone and emitting alpha-particles with energies in the range 3-8 MeV. These results are used to demonstrate that on an activity basis 239Pu is unlikely to be more than fifteen times as toxic as 226Ra with respect to osteosarcoma and leukaemia induction in man.
本文讨论了骨中发射α粒子的放射性核素的剂量学。给出了放射性核素薄平面源埋入骨中不同深度并发射能量在3 - 8 MeV范围内α粒子时，靠近骨内膜表面的组织和造血骨髓的平均剂量率结果。这些结果用于证明，就活性而言，在诱发人类骨肉瘤和白血病方面，239Pu的毒性不可能比226Ra大15倍以上。
