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肺炎球菌结合疫苗免疫接种对急性中耳炎中肺炎链球菌耐药模式的影响。

The effect of immunization with pneumococcal conjugated vaccines on Streptococcus pneumoniae resistance patterns in acute otitis media.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Edith Wolfson Medical Center, Tel Aviv University Sackler School of Medicine, Holon, Israel.

Faculty of Medicine, Tel Aviv University Sackler School of Medicine, Tel Aviv, Israel.

出版信息

J Microbiol Immunol Infect. 2017 Oct;50(5):714-717. doi: 10.1016/j.jmii.2015.08.009. Epub 2015 Sep 9.

Abstract

Following the introduction of 7- and 13-pneumococcal conjugate vaccines (PCVs) in Israel, we demonstrated that within Streptococcus pneumoniae (Sp) positive middle ear cultures, obtained from young children with severe acute otitis media (AOM) episodes, there were more penicillin-susceptible and less multi-drug resistant Sp isolates in PCV immunized children.

摘要

在以色列推出 7 价和 13 价肺炎球菌结合疫苗(PCV)后,我们证实,在因重度急性中耳炎(AOM)发作而从幼儿中获得的肺炎链球菌(Sp)阳性中耳培养物中,PCV 免疫儿童的青霉素敏感性 Sp 分离株更多,而多药耐药性 Sp 分离株更少。

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