Chung Sung Jun, Koo Gun Woo, Park Dong Won, Kwak Hyun Jung, Yhi Ji Young, Moon Ji-Yong, Kim Sang-Heon, Sohn Jang Won, Yoon Ho Joo, Shin Dong Ho, Park Sung Soo, Pyo Ju Yeon, Oh Young-Ha, Kim Tae-Hyung
Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Department of Pathology, Hanyang University College of Medicine, Seoul, Korea.
Tuberc Respir Dis (Seoul). 2015 Oct;78(4):445-9. doi: 10.4046/trd.2015.78.4.445. Epub 2015 Oct 1.
Occupational lung diseases are caused by several toxic substances including heavy metals; however, the exact pathologic mechanisms remain unknown. In the workplace, dental technicians are often exposed to heavy metals such as cobalt, nickel, or beryllium and occasionally develop occupational lung diseases. We described a case of occupational lung disease in a patient who was employed as a dental technician for over a decade. A 31-year-old, non-smoking woman presented with productive cough and shortness of breath of several weeks duration. Chest computed tomography revealed a large number of scattered, bilateral small pulmonary nodules throughout the lung field, and multiple mediastinal lymph nodes enlargement. Percutaneous needle biopsy showed multifocal small granulomas with foreign body type giant cells suggestive of heavy metals inhalation. The patient's condition improved on simple avoidance strategy for several months. This case highlighted the importance of proper workplace safety.
职业性肺病由包括重金属在内的多种有毒物质引起;然而,确切的病理机制仍不清楚。在工作场所,牙科技术员经常接触钴、镍或铍等重金属,偶尔会患上职业性肺病。我们描述了一例从事牙科技术员工作十多年的患者患职业性肺病的病例。一名31岁的不吸烟女性出现持续数周的咳痰和气短症状。胸部计算机断层扫描显示双肺野有大量散在的小结节,以及多个纵隔淋巴结肿大。经皮针吸活检显示多灶性小肉芽肿,伴有异物型巨细胞,提示吸入重金属。通过简单的避免接触策略,患者的病情在几个月内有所改善。该病例凸显了适当的工作场所安全的重要性。