Giannis Georg, Bousouni Evgenia, Mueller Michael D, Imboden Sara, Mohr Stefan, Raio Luigi, Kuhn Annette
Kantonsspital Schaffhausen, Switzerland.
Kantonsspital Aarau, Switzerland.
Eur J Obstet Gynecol Reprod Biol. 2015 Dec;195:103-107. doi: 10.1016/j.ejogrb.2015.09.033. Epub 2015 Oct 17.
Bladder outlet obstruction may occur after any incontinence surgery and may present as OAB, hesitancy and or the feeling of incomplete emptying. Aim of this study was to analyze the clinical and urodynamical outcome after urethrolysis in patients presenting with various clinical symptoms after Burch colposuspension for stress urinary incontinence.
Between January 2005 and December 2014, all patients who presented with symptoms and with bladder outlet obstruction were included. All patients had undergone Burch or Cowan colposuspension for stress urinary incontinence previously. Primary endpoint was the visual analogue scale (VAS) as measurement of patient perceived disease impact. Secondary endpoints were the various domains of the King's Health Questionnaire, urodynamic parameters as detrusor pressure at maximum flow, residual urine and sonographic bladder wall thickness before and six months after intervention.
Seventy-two female patients were included in this study whereof 42 suffered from urgency and urge incontinence, 20 from hesitancy and/or slow stream, seven from residual urine of more than 100ml and three from a combination of urgency and residual urine. VAS improved significantly (p<0.0001). Quality of life as determined by the King's Health Questionnaire improved for the domains general health, role limitations, emotions, physical limitations, personal limitations and incontinence impact significantly. Micturition pressure dropped significantly from 43cmH2O (95% CI 19-59cmH2O) to 18cmH2O (95% CI 16-23.5 H2O). Residual urine changed from 110ml (range 20-380ml) to 32ml (20-115ml). Bladder wall thickness decreased from 7mm (95% CI 6.235-7.152) to 5mm (95% CI 5.037-5.607; p<0.01).
Urethrolysis may resolve patients' symptoms and lower micturition pressure but irritative symptoms may persist.
任何尿失禁手术后都可能发生膀胱出口梗阻,其表现可能为膀胱过度活动症、排尿犹豫和/或排空不全感。本研究的目的是分析因压力性尿失禁行Burch阴道膀胱悬吊术后出现各种临床症状的患者行尿道松解术后的临床及尿动力学结果。
2005年1月至2014年12月期间,纳入所有出现症状且存在膀胱出口梗阻的患者。所有患者此前均因压力性尿失禁接受过Burch或Cowan阴道膀胱悬吊术。主要终点是视觉模拟量表(VAS),用于衡量患者感知到的疾病影响。次要终点是国王健康问卷的各个领域、尿动力学参数,如最大尿流时的逼尿肌压力、残余尿量以及干预前和干预后六个月的超声膀胱壁厚度。
本研究纳入了72名女性患者,其中42名患有尿急和急迫性尿失禁,20名患有排尿犹豫和/或尿流缓慢,7名残余尿量超过100ml,3名同时患有尿急和残余尿量。VAS显著改善(p<0.0001)。国王健康问卷所确定的生活质量在总体健康、角色限制、情绪、身体限制、个人限制和尿失禁影响等领域显著改善。排尿压力从43cmH2O(95%可信区间19 - 59cmH2O)显著降至18cmH2O(95%可信区间16 - 23.5H2O)。残余尿量从110ml(范围20 - 380ml)变为32ml(20 - 115ml)。膀胱壁厚度从7mm(95%可信区间6.235 - 7.152)降至5mm(95%可信区间5.037 - 5.607;p<0.01)。
尿道松解术可缓解患者症状并降低排尿压力,但刺激性症状可能持续存在。