Lai Chih-Hung, Chang Szu-Ling, Lin Wei-Wen, Hsiung Ming-Chon, Juan Yu-Hsiang, Wang Tzu-Lin
From the Division of Interventional Cardiology, Cardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan, ROC (C-HL, W-WL); Department of Anesthesiology, Taichung Veterans General Hospital, Taichung, Taiwan, ROC (S-LC); Division of Cardiovascular Disease, Cheng-Hsin General Hospital, Taipei, Taiwan, ROC (M-CH); Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou and Chang Gung University, Taoyuan, Taiwan, ROC (Y-HJ); Healthy Aging Research Center, Chang Gung University, Taiwan, ROC (Y-HJ); Division of Cardiology, Department of Internal Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan, ROC (T-LW); and Institute of Emergency and Critical Care Medicine, National Yang-Ming University, Taipei, Taiwan, ROC (C-HL, S-LC, T-LW).
Medicine (Baltimore). 2015 Oct;94(43):e1844. doi: 10.1097/MD.0000000000001844.
Hypereosinophilic syndrome (HES) describes a disorder characterized by persistent peripheral blood eosinophilia with evidence of multiple target organs damage caused by eosinophilia. HES most commonly involves the heart, and cardiac involvement typically presents in the form of endomyocarditis or myocarditis with apical mural thrombus formation.We present a case with atypical cardiac presentation with massive intracardiac fragile thrombi, causing peripheral emboli and strokes.HES can present as floating thrombi with thin attachment to the left ventricle, and clinicians should also be vigilant of thromboembolic complications and initiate early therapy to prevent or reduce the potential complications of HES.
高嗜酸性粒细胞综合征（HES）是一种以持续性外周血嗜酸性粒细胞增多为特征的疾病，并有嗜酸性粒细胞增多导致多靶器官损害的证据。HES最常累及心脏，心脏受累通常表现为心内膜炎或心肌炎伴心尖壁血栓形成。我们报告一例具有非典型心脏表现的病例，其心脏内有大量易碎血栓，导致外周栓塞和中风。HES可表现为与左心室有薄附着的漂浮血栓，临床医生也应警惕血栓栓塞并发症，并尽早开始治疗以预防或减少HES的潜在并发症。
