Balsamo Lyn M, Sint Kyaw J, Neglia Joseph P, Brouwers Pim, Kadan-Lottick Nina S
Section of Pediatric Hematology/Oncology, Yale University School of Medicine
School of Public Health, Yale University.
J Pediatr Psychol. 2016 Apr;41(3):319-28. doi: 10.1093/jpepsy/jsv103. Epub 2015 Oct 29.
Assess the association between fine motor (FM) and visual-motor integration (VMI) skills and academic achievement in pediatric acute lymphoblastic leukemia (ALL) survivors.
In this 28-site cross-sectional study of 256 children in first remission, a mean of 8.9 ± 2.2 years after treatment for standard-risk precursor-B ALL, validated measures of FM, VMI, reading, math, and intelligence were administered at mean follow-up age of 12.8 ± 2.5 years.
VMI was significantly associated with written math calculation ability (p < .0069) after adjusting for intelligence (p < .0001). VMI was more strongly associated with math in those with lower intelligence (p = .0141). Word decoding was also significantly associated with VMI but with no effect modification by intelligence. FM skills were not associated with either reading or math achievement.
These findings suggest that VMI is associated with aspects of math and reading achievement in leukemia survivors. These skills may be amenable to intervention.
评估小儿急性淋巴细胞白血病（ALL）幸存者的精细运动（FM）和视动整合（VMI）技能与学业成绩之间的关联。
在这项涉及28个地点的横断面研究中，对256名处于首次缓解期的儿童进行了研究，这些儿童在接受标准风险前体B型ALL治疗后平均8.9±2.2年，在平均随访年龄12.8±2.5岁时进行了FM、VMI、阅读、数学和智力的有效测量。
在调整智力因素（p<0.0001）后，VMI与书面数学计算能力显著相关（p<0.0069）。在智力较低的人群中，VMI与数学的相关性更强（p=0.0141）。单词解码也与VMI显著相关，但不受智力因素的影响。FM技能与阅读或数学成绩均无关联。
这些发现表明，VMI与白血病幸存者的数学和阅读成绩方面相关。这些技能可能适合进行干预。
