Demirhan Hasan, Acioğlu Engin, Durna Yusuf Muhammed, Yiğit Özgür, Bozkurt Erol Rüştü, Karagöz Yeşim
*Ear Nose and Throat Clinic †Pathology Clinic ‡Department of Otorhinolaryngology, Radiology Clinic, Istanbul Training and Research Hospital, Istanbul, Turkey.
J Craniofac Surg. 2015 Nov;26(8):e689-90. doi: 10.1097/SCS.0000000000002052.
Chondroblastoma is a highly destructive tumor originating from immature cartilage cells. Although chondroblastoma is defined as a benign tumor, it may exhibit malign tumor behaviors such as invasion or metastasis on neighboring structures. Magnetic resonance (MR) image is a solid mass lesion, which included heterogeneous hypointense in T2A and heterogeneous minimal hyperintense in T1A with destructive expansile characteristics and millimetric calcifications. Temporal bone chondroblastomas may complicate the diagnosis because of their different histologic characteristics. Microscopically, chondroblastic cell nests and calcification of locally "chicken wire" type around the cells are observed. These tumors secrete s-100 and vimentin and are used for differential diagnosis. In this study, a temporal bone localized chondroblastoma case is presented.
软骨母细胞瘤是一种起源于未成熟软骨细胞的高度破坏性肿瘤。尽管软骨母细胞瘤被定义为良性肿瘤,但它可能表现出侵袭或转移至邻近结构等恶性肿瘤行为。磁共振(MR)图像显示为实性肿块病变,在T2A序列中呈不均匀低信号,在T1A序列中呈不均匀轻度高信号,具有破坏性膨胀性特征和毫米级钙化。颞骨软骨母细胞瘤因其不同的组织学特征可能使诊断复杂化。在显微镜下,可观察到软骨母细胞巢以及细胞周围局部呈“鸡笼”样的钙化。这些肿瘤分泌S-100和波形蛋白,可用于鉴别诊断。在本研究中,报告了一例颞骨局限性软骨母细胞瘤病例。