Bruyneel M, Haumont S, Devuyst F
Service de pneumologie, CHU Saint-Pierre, 322, rue Haute, 1000 Bruxelles, Belgique.
Service d'endocrinologie, hôpital Erasme, université libre de Bruxelles, 1000 Bruxelles, Belgique.
Rev Mal Respir. 2016 May;33(5):405-8. doi: 10.1016/j.rmr.2015.07.002. Epub 2015 Oct 27.
Acromegaly is a rare hormonal disease related to excessive growth hormone secretion. It can result in a range of complications, including cardiovascular, respiratory, metabolic, articular and neoplastic disorders. Among patients with the condition, obstructive sleep apnea syndrome occurs frequently and the effect of treatment is inconstant: improvement, statu quo or deterioration can be observed. We here report three clinical cases, which illustrate the unpredictable evolution of this condition.
肢端肥大症是一种与生长激素分泌过多相关的罕见激素疾病。它可导致一系列并发症，包括心血管、呼吸、代谢、关节和肿瘤性疾病。在患有这种疾病的患者中，阻塞性睡眠呼吸暂停综合征经常发生，且治疗效果不稳定：可观察到病情改善、维持现状或恶化。我们在此报告三例临床病例，以说明这种疾病不可预测的病程。
