Lux G
Klinik für Gastroenterologie und allgemeine Innere Medizin Städtisches Krankenhaus Solingen.
Leber Magen Darm. 1989 Mar;19(2):84-93.
Diabetic motility disturbances are frequent and may be found within esophagus, stomach, small bowel, colon and anal sphincter. Disturbed motility may explain gastrointestinal symptoms of patients with diabetic enteropathy, but there is no correlation between symptoms and extent of motility changes. Prokinetic drugs relief symptoms, but also without improving motility parameters. Diarrhea is best treated by local opoid agonists (loperamide), in anorectal incontinence biofeedback training is also to be recommended.
糖尿病性运动障碍很常见,可出现在食管、胃、小肠、结肠和肛门括约肌。运动障碍可能解释糖尿病性肠病患者的胃肠道症状,但症状与运动变化程度之间并无关联。促动力药物可缓解症状,但也无法改善运动参数。腹泻最好用局部阿片类激动剂(洛哌丁胺)治疗,对于肛门直肠失禁,生物反馈训练也值得推荐。