Febrero B, Ramírez P, Espinosa F, Rodríguez J M, Ríos A, Robles R, Sánchez-Bueno F, Cascales P, Luján J, Parrilla P
Transplant Unit, Department of General Surgery, Virgen de la Arrixaca University Hospital, Murcia, Spain; Instituto Murciano de Investigaciones Biomédicas (IMIB), Department of Surgery, University of Murcia, Murcia, Spain.
Transplant Unit, Department of General Surgery, Virgen de la Arrixaca University Hospital, Murcia, Spain; Instituto Murciano de Investigaciones Biomédicas (IMIB), Department of Surgery, University of Murcia, Murcia, Spain; Regional Transplant Center, Consejería de Sanidad y Consumo de la Región de Murcia, Murcia, Spain.
Transplant Proc. 2015 Oct;47(8):2385-7. doi: 10.1016/j.transproceed.2015.08.034.
Obesity is a risk factor that increases the number of complications after orthotopic liver transplantation (LT). We sought to analyze the short-term respiratory complications in obese LT recipients and compare them with a control group of nonobese patients.
A retrospective analysis of LT patients in a hospital in the southeast of Spain (2007-2013), selecting the study cases using a body mass index (BMI) of >30 kg/m(2) and a control group (BMI < 30). Study variables were age, sex, indication for LT, demographic and clinical variables, respiratory complications during the first postoperative month, and mortality rate secondary to respiratory disease.
Of the 343 LT recipients, 74 were obese (21.6%): 59 patients had a BMI between 30 and 35 (grade I obesity) and among them, 5% presented with respiratory complications, with a 33% mortality rate. Fifteen patients had a BMI of >35 (obesity grade II), and 20% presented with respiratory complications, with a 33% mortality rate. In the control group (n = 30), 17% experienced respiratory complications and there was a 20% mortality rate. There were no differences in respiratory complications between the obese and nonobese groups, or the different kinds of obesity (P > .05).
There were no differences in short-term respiratory complications between obese LT recipients and those with a normal weight.
肥胖是原位肝移植（LT）术后并发症增多的一个风险因素。我们试图分析肥胖肝移植受者的短期呼吸并发症，并将其与非肥胖患者的对照组进行比较。
对西班牙东南部一家医院的肝移植患者进行回顾性分析（2007 - 2013年），采用体重指数（BMI）>30 kg/m²选择研究病例，并设对照组（BMI < 30）。研究变量包括年龄、性别、肝移植指征、人口统计学和临床变量、术后第一个月的呼吸并发症以及呼吸系统疾病导致的死亡率。
在343例肝移植受者中，74例为肥胖患者（21.6%）：59例患者的BMI在30至35之间（I级肥胖），其中5%出现呼吸并发症，死亡率为33%。15例患者的BMI>35（II级肥胖），20%出现呼吸并发症，死亡率为33%。在对照组（n = 30）中，17%出现呼吸并发症，死亡率为20%。肥胖组与非肥胖组之间以及不同类型肥胖之间的呼吸并发症无差异（P > 0.05）。
肥胖肝移植受者与体重正常者在短期呼吸并发症方面无差异。
