Robert Koch Institute, Dept. of Epidemiology and Health Monitoring, Berlin, Germany; Institute for Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany.
Robert Koch Institute, Dept. of Epidemiology and Health Monitoring, Berlin, Germany; Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.
J Affect Disord. 2016 Jan 15;190:167-177. doi: 10.1016/j.jad.2015.10.006. Epub 2015 Oct 24.
While standardized diagnostic interviews using established criteria are the gold standard for assessing depression, less time consuming measures of depression and depressive symptoms are commonly used in large population health surveys. We examine the prevalence and health-related correlates of three depression measures among adults aged 18-79 years in Germany.
Using cross-sectional data from the national German Health Interview and Examination Survey for Adults (DEGS1) (n=7987) and its mental health module (DEGS1-MH) (n=4483), we analysed prevalence and socio-demographic and health-related correlates of (a) major depressive disorder (MDD) established by Composite International Diagnostic Interview (CIDI) using DSM-IV-TR criteria (CIDI-MDD) in the last 12 months, (b) self-reported physician or psychotherapist diagnosed depression in the last 12 months, and (c) current depressive symptoms in the last two weeks (PHQ-9, score ≥10).
Prevalence of 12-month CIDI-MDD was 4.2% in men and 9.9% in women. Prevalence of 12-month self-reported health professional-diagnosed depression was 3.8% and 8.1% and of current depressive symptoms 6.1% and 10.2% in men and women, respectively. Case-overlap between measures was only moderate (32-45%). In adjusted multivariable analyses, depression according to all three measures was associated with lower self-rated health, lower physical and social functioning, higher somatic comorbidity (except for women with 12-month CIDI-MDD), more sick leave and higher health service utilization.
Persons with severe depression may be underrepresented. Associations between CIDI-MDD and correlates and overlap with other measures may be underestimated due to time lag between DEGS1 and DEGS1-MH.
Prevalence and identified cases varied between these three depression measures, but all measures were consistently associated with a wide range of adverse health outcomes.
虽然使用既定标准的标准化诊断访谈是评估抑郁症的金标准,但在大型人群健康调查中,通常使用耗时较少的抑郁症和抑郁症状测量方法。我们研究了德国 18-79 岁成年人中三种抑郁症测量方法的流行程度和与健康相关的相关性。
我们使用全国德国成人健康访谈和体检调查(DEGS1)(n=7987)及其心理健康模块(DEGS1-MH)(n=4483)的横断面数据,分析了(a)使用 DSM-IV-TR 标准在过去 12 个月内通过复合国际诊断访谈(CIDI)确定的主要抑郁症障碍(MDD)(CIDI-MDD)、(b)在过去 12 个月内自我报告的医生或心理治疗师诊断的抑郁症以及(c)过去两周内的当前抑郁症状(PHQ-9,得分≥10)的患病率及其与社会人口统计学和健康相关的相关性。
男性 12 个月 CIDI-MDD 的患病率为 4.2%,女性为 9.9%。男性和女性 12 个月自我报告的卫生专业人员诊断的抑郁症患病率分别为 3.8%和 8.1%,当前抑郁症状的患病率分别为 6.1%和 10.2%。三种测量方法之间的重叠仅为中等(32-45%)。在调整后的多变量分析中,根据所有三种测量方法确定的抑郁症与自评健康状况较差、身体和社会功能较低、躯体共病较多(女性 12 个月 CIDI-MDD 除外)、请病假较多和更多使用卫生服务有关。
可能存在严重抑郁症患者人数不足的情况。由于 DEGS1 和 DEGS1-MH 之间存在时间滞后,CIDI-MDD 与相关性之间的关联以及与其他测量方法的重叠可能被低估。
这三种抑郁症测量方法的患病率和确定的病例各不相同,但所有方法都与广泛的不良健康结果一致相关。