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国际机械循环辅助装置注册研究(INTERMACS)第七年度报告:15000例患者及仍在增加。

Seventh INTERMACS annual report: 15,000 patients and counting.

作者信息

Kirklin James K, Naftel David C, Pagani Francis D, Kormos Robert L, Stevenson Lynne W, Blume Elizabeth D, Myers Susan L, Miller Marissa A, Baldwin J Timothy, Young James B

机构信息

Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.

Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.

出版信息

J Heart Lung Transplant. 2015 Dec;34(12):1495-504. doi: 10.1016/j.healun.2015.10.003. Epub 2015 Oct 8.

DOI:10.1016/j.healun.2015.10.003
PMID:26520247
Abstract

The seventh annual report of the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) summarizes the first 9 years of patient enrollment. The Registry includes >15,000 patients from 158 participating hospitals. Trends in device strategy, patient profile at implant and survival are presented. Risk factors for mortality with continuous-flow pumps are updated, and the major causes/modes of death are presented. The adverse event burden is compared between eras, and health-related quality of life is reviewed. A detailed analysis of outcomes after mechanical circulatory support for ambulatory heart failure is presented. Recent summary data from PediMACS and MedaMACS is included. With the current continuous-flow devices, survival at 1 and 2 years is 80% and 70%, respectively.

摘要

机构间机械辅助循环支持注册中心(INTERMACS)的第七份年度报告总结了患者入组的前9年情况。该注册中心纳入了来自158家参与医院的15000多名患者。报告呈现了设备策略、植入时患者概况及生存情况的趋势。更新了连续流泵相关的死亡风险因素,并列出了主要死亡原因/方式。比较了不同时期的不良事件负担,并对健康相关生活质量进行了回顾。还对门诊心力衰竭患者接受机械循环支持后的结局进行了详细分析。纳入了儿科机械辅助循环支持注册中心(PediMACS)和孕产妇机械辅助循环支持注册中心(MedaMACS)的近期汇总数据。使用当前的连续流设备,1年和2年生存率分别为80%和70%。

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