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Unusual Presentation of Cerebral Cavernous Malformation.

作者信息

Kim Won-Hyung, Lim Dong-Jun, Choi Jong-Il, Ha Sung-Kon, Kim Sang-Dae, Kim Se-Hoon

机构信息

Department of Neurosurgery, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.

出版信息

J Cerebrovasc Endovasc Neurosurg. 2015 Sep;17(3):257-62. doi: 10.7461/jcen.2015.17.3.257. Epub 2015 Sep 30.

DOI:10.7461/jcen.2015.17.3.257
PMID:26523262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4626352/
Abstract

Cerebral cavernous malformations (CMs) are vascular malformations of the central nervous system, which can be detected in the absence of any clinical symptoms. Nodules and cysts with mixed signal intensity and a peripheral hemosiderin rim are considered brain magnetic resonance imaging (MRI) findings typical of CMs. A 48-year-old man was admitted to our hospital because of abnormal MRI findings without significant neurological symptoms. A cyst with an internal fluid-fluid level was found in the left basal ganglia on the initial brain MRI. We decided to observe the natural course of the asymptomatic lesion with serial MRI follow-up. On MRI at the 5-month follow-up, the cystic mass was enlarged and showed findings consistent with those of cystic CM. Surgical resection was performed and the pathological diagnosis was CM. Our experience suggests that the initial presentation of a CM can be a pure cyst and neurosurgeons should consider the likelihood of CMs in cases of cystic cerebral lesions with intracystic hemorrhage.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e9/4626352/b58ae59b4c18/jcen-17-257-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e9/4626352/63ff29779e3d/jcen-17-257-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e9/4626352/7f8cdf893cd8/jcen-17-257-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e9/4626352/b58ae59b4c18/jcen-17-257-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e9/4626352/63ff29779e3d/jcen-17-257-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e9/4626352/7f8cdf893cd8/jcen-17-257-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1e9/4626352/b58ae59b4c18/jcen-17-257-g003.jpg

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本文引用的文献

1
Treatment of cerebral cavernous malformations: a systematic review and meta-regression analysis.脑动静脉畸形的治疗:系统评价和荟萃回归分析。
J Neurol Neurosurg Psychiatry. 2014 Dec;85(12):1319-23. doi: 10.1136/jnnp-2013-307349. Epub 2014 Mar 25.
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Giant cystic cerebral cavernous malformation with multiple calcification - case report.巨大囊性脑海绵状畸形伴多发钙化——病例报告
J Cerebrovasc Endovasc Neurosurg. 2013 Sep;15(3):255-9. doi: 10.7461/jcen.2013.15.3.255. Epub 2013 Sep 30.
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Cavernous malformation of brainstem, thalamus, and basal ganglia: a series of 176 patients.
囊性脑海绵状畸形:5例报告及文献复习
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脑干、丘脑和基底节海绵状血管畸形:176 例患者系列。
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Neurosurg Rev. 2010 Oct;33(4):395-400. doi: 10.1007/s10143-010-0245-x. Epub 2010 Feb 20.
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Intracranial cysts: radiologic-pathologic correlation and imaging approach.颅内囊肿:放射学与病理学的相关性及影像学检查方法
Radiology. 2006 Jun;239(3):650-64. doi: 10.1148/radiol.2393050823.
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Value of gradient-echo magnetic resonance imaging in the diagnosis of familial cerebral cavernous malformation.梯度回波磁共振成像在家族性脑海绵状血管畸形诊断中的价值
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