Pfaff W W, Sanfilippo F, Lucas B A, Vaughn W K
South Eastern Organ Procurement Foundation (SEOPF), Richmond, Virginia 23226.
Transplant Proc. 1989 Feb;21(1 Pt 2):1405-7.
A voluntary system was created to foster early sharing of well-matched organs between like-minded renal transplantation programs. In the two historic periods 1982-85 and 1985-86, sharing programs (Category I & II) and nonsharing programs (Category III) had similar graft survival. In the study period 1986-88, graft survival improved in Category I and II programs and was unchanged in Category III programs. Highly sensitized recipients in sharing programs had an incremental gain of 15.0%, patients receiving multiple grafts 12.6%. Grafts derived from local donors and transplants in less sensitized patients also were improved but for less obvious reasons. The implementation of this study was followed by a slight decrement in delayed graft function. It is our conclusion that early graft sharing can result in improved overall early graft survival.
建立了一个自愿系统，以促进志同道合的肾移植项目之间早期共享匹配良好的器官。在1982 - 1985年和1985 - 1986年这两个历史时期，共享项目（第一类和第二类）和非共享项目（第三类）的移植肾存活率相似。在1986 - 1988年的研究期间，第一类和第二类项目的移植肾存活率有所提高，而第三类项目则没有变化。共享项目中高度致敏受者的移植肾存活率提高了15.0%，接受多次移植的患者提高了12.6%。来自本地供者的移植肾以及致敏程度较低患者的移植肾也有所改善，但原因不太明显。这项研究实施后，移植肾功能延迟略有下降。我们的结论是，早期移植肾共享可提高总体早期移植肾存活率。
