Ikeda Kei
Rinsho Byori. 2015 May;63(5):580-9.
Inflammation of soft tissues and the subsequent structural damage are the characteristic features of many rheumatic conditions. However, the conventional measures to evaluate these features are not accurate, potentially causing under- and over-diagnosis or treatment. Musculoskeletal ultrasonography, on the other hand, directly visualizes features which are characteristic to rheumatic conditions, such as synovitis, tenosynovitis, bursitis, enthesitis, crystal depositions, bone erosions, and osteophytes/enthesophytes. By visualizing these key features, ultrasound facilitates a more accurate evaluation of rheumatic diseases such as rheumatoid arthritis (RA), spondyloarthropathy, crystal-induced arthritis, and osteoarthritis. For RA, we investigated the impact of ultrasound on the 2010 ACR/EULAR RA classification criteria when joint involvement was determined. We assessed 109 patients with early arthritis using ultrasound. When the presence of joint swelling and number of involved joints were determined by ultrasound, the classification of RA was different from that without ultrasound in approximately 20% of the patients. Moreover, the accuracy of the classification to identify patients who required methotrexate treatment within a year improved by ultrasound. In addition, we and other investigators demonstrated the advantage of ultrasound over conventional measures in the assessment of disease activity of RA. Ultrasound also supports the education of both physicians and patients and communication between them. The utilization of musculoskeletal ultrasonography in more hospitals and clinics is expected to improve the quality of daily practice for rheumatic diseases.
软组织炎症及随后的结构损伤是许多风湿性疾病的特征性表现。然而,评估这些特征的传统方法并不准确,可能导致诊断不足或过度诊断及治疗。另一方面,肌肉骨骼超声可直接显示风湿性疾病的特征性表现,如滑膜炎、腱鞘炎、滑囊炎、附着点炎、晶体沉积、骨质侵蚀和骨赘/附着点骨赘。通过显示这些关键特征,超声有助于更准确地评估类风湿关节炎(RA)、脊柱关节炎、晶体性关节炎和骨关节炎等风湿性疾病。对于RA,我们研究了在确定关节受累情况时超声对2010年美国风湿病学会/欧洲抗风湿病联盟(ACR/EULAR)RA分类标准的影响。我们使用超声评估了109例早期关节炎患者。当通过超声确定关节肿胀的存在和受累关节数量时,约20%的患者RA的分类与未使用超声时不同。此外,超声提高了在一年内识别需要甲氨蝶呤治疗的患者的分类准确性。此外,我们和其他研究人员证明了超声在评估RA疾病活动度方面优于传统方法。超声还有助于医生和患者的教育以及他们之间的沟通。预计在更多医院和诊所使用肌肉骨骼超声将提高风湿性疾病日常诊疗的质量。