Zhang Shu, Yan Huan, Ji Wen-Ting
Department of Obstetrics and Gynecology, RenJi Hospital, Shanghai Jiao-Tong University School of Medicine, 1630 Dong Fang Road, Shanghai, 200127, China.
Arch Gynecol Obstet. 2016 May;293(5):1043-7. doi: 10.1007/s00404-015-3929-1. Epub 2015 Nov 2.
To investigate the efficacy and safety of uterine artery chemoembolization (UAE) combined with intra-arterial MTX infusion for the treatment of cervical pregnancy.
Retrospective chart review for 26 cervical pregnancy patients treated at Renji hospital between January 2000 and December 2012. 14 patients received UAE combined with intra-arterial MTX infusion (UAE group) and 12 patients received single intramuscular MTX injection combined with subsequent uterine curettage (non-UAE group).
All 14 patients in the UAE group were treated successfully and 1 patient in the non-UAE group had 1200 ml vaginal bleeding during uterine curettage and was then treated with emergency UAE. The mean estimated blood loss during uterine curettage in the UAE group was much less than in non-UAE Group. A quicker regression of serum β-hCG level and normal menses resumed and a shorter hospital stay were observed in the UAE group than in the non-UAE group.
Uterine artery chemoembolization combined with intra-arterial MTX infusion is an efficient conservative treatment for cervical pregnancy.
探讨子宫动脉化疗栓塞术（UAE）联合动脉内甲氨蝶呤（MTX）灌注治疗宫颈妊娠的疗效及安全性。
回顾性分析2000年1月至2012年12月在仁济医院治疗的26例宫颈妊娠患者的病历。14例患者接受UAE联合动脉内MTX灌注（UAE组），12例患者接受单次肌内注射MTX联合后续刮宫术（非UAE组）。
UAE组14例患者均治疗成功，非UAE组1例患者在刮宫术中出现1200 ml阴道出血，随后接受急诊UAE治疗。UAE组刮宫术中估计平均失血量远少于非UAE组。与非UAE组相比，UAE组血清β-hCG水平下降更快，月经恢复正常，住院时间更短。
子宫动脉化疗栓塞术联合动脉内MTX灌注是治疗宫颈妊娠的一种有效的保守治疗方法。
