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胰腺胰岛素瘤。病例报告及文献综述。

Pancreatic insulinoma. Case report and review of the literature.

作者信息

Negrean Vasile, Tudor Andra, Aioanei Oana, Domsa Iacob

机构信息

Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca ; University Hospital CF, Cluj-Napoca.

University Hospital CF, Cluj-Napoca.

出版信息

Clujul Med. 2013;86(4):377-9. Epub 2013 Nov 6.

PMID:26527982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4462452/
Abstract

Insulinoma is a rare pancreatic islet cell tumor, the most common cause of hypoglycemia related to endogenous hyperinsulinism. We present the case of an adult patient with pancreatic insulinoma. The patient presented to our clinic after prior hospitalizations in diabetes and psychiatry hospital units for repeated episodes of loss of consciousness, sweating and tonic-clonic seizures. Early detection of the cause is important for prompt initiation of therapy and to reduce symptoms. We describe our diagnostic and therapeutic strategies with references to previously published reports.

摘要

胰岛素瘤是一种罕见的胰岛细胞瘤,是内源性高胰岛素血症相关低血糖最常见的病因。我们报告一例成年胰腺胰岛素瘤患者。该患者此前因反复出现意识丧失、出汗和强直阵挛发作,曾入住糖尿病和精神病医院科室,之后前来我们诊所就诊。尽早查明病因对于及时开始治疗和减轻症状很重要。我们参照先前发表的报告描述了我们的诊断和治疗策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c183/4462452/1206b4a9c5e9/cm-86-377f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c183/4462452/192853d09c7d/cm-86-377f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c183/4462452/0437630e7624/cm-86-377f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c183/4462452/1206b4a9c5e9/cm-86-377f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c183/4462452/192853d09c7d/cm-86-377f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c183/4462452/0437630e7624/cm-86-377f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c183/4462452/1206b4a9c5e9/cm-86-377f3.jpg

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Pancreatic insulinoma. Case report and review of the literature.胰腺胰岛素瘤。病例报告及文献综述。
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引用本文的文献

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Picking up an insulinoma - The challenges ahead.发现胰岛素瘤——未来的挑战
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A Rare Case of Insulinoma in a Thin, Lean Adult Male: A Case Report.一例瘦成年男性胰岛素瘤罕见病例:病例报告
Cureus. 2022 Mar 23;14(3):e23414. doi: 10.7759/cureus.23414. eCollection 2022 Mar.
3
Diagnostic challenges in a patient with an occult insulinoma:Ga-DOTA-exendin-4 PET/CT and Ga-DOTATATE PET/CT.隐匿性胰岛素瘤患者的诊断挑战:镓标记的exendin-4正电子发射断层显像/计算机断层扫描(Ga-DOTA-exendin-4 PET/CT)和镓标记的奥曲肽正电子发射断层显像/计算机断层扫描(Ga-DOTATATE PET/CT)

本文引用的文献

1
Insulinoma--experience from 1950 to 1995.胰岛素瘤——1950年至1995年的经验
West J Med. 1998 Aug;169(2):98-104.
2
[Insulinomas--nesidioblastomas. Clinical experience].[胰岛素瘤——胰岛细胞增生症。临床经验]
Chirurgia (Bucur). 1997 Nov-Dec;92(6):387-97.
3
Prognostic value of Ki-67 expression, ploidy and S-phase fraction in patients with pancreatic cancer.Ki-67表达、倍体及S期分数在胰腺癌患者中的预后价值
Clin Case Rep. 2018 Mar 1;6(4):719-722. doi: 10.1002/ccr3.1448. eCollection 2018 Apr.
4
Vague neuroglycopenic complaints camouflage diagnosis of adolescent insulinoma: a case report.模糊的神经低血糖症状掩盖了青少年胰岛素瘤的诊断:一例报告
Int J Pediatr Endocrinol. 2016;2016:14. doi: 10.1186/s13633-016-0032-8. Epub 2016 Jul 29.
Anticancer Res. 1995 Nov-Dec;15(6B):2659-68.
4
Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study.功能性胰岛素瘤——患者的发病率、复发率及长期生存率:一项60年的研究
Mayo Clin Proc. 1991 Jul;66(7):711-9. doi: 10.1016/s0025-6196(12)62083-7.