Elec Florin Ioan, Lucan Ciprian, Ghervan Liviu, Munteanu Valentin, Moga Silviu, Suciu Mihai, Enache Dan, Elec Alina, Munteanu Adriana, Barbos Adrian, Iacob Gheorghita, Lucan Mihai
Clinical Institute of Urology and Renal Transplantation Cluj-Napoca.
Clujul Med. 2014;87(1):27-9. doi: 10.15386/cjm.2014.8872.871.fie1. Epub 2014 Jan 30.
With a growing shortage of organs for transplantation, finding ways of increasing the donor organ pool remains of utmost importance. Perfusion machines (PM) have been proven to enhance the potential for kidney transplants to function sooner, last longer, giving patients the opportunity for a better life quality.
The aim of this study is to evaluate the relation between the resistance index provided by the PM, the postoperative resistance index measured by Doppler ultrasound and the initial graft outcome.
Between January 2012-December 2012, clinical data obtained from 82 consecutive renal transplants from brain death donors (BDD) which underwent PM maintenance were analyzed in a transversal study. Prior transplantation we recorded the solution temperature, filtration rate and the resistance index provided by PM. After the surgical intervention, each patient had standard follow-up. Doppler ultrasound resistivity index (RI) was recorded on the first postoperative day.
Out of 115 renal transplants, 98 (85.21%) were performed with grafts from BDD. The PM was used for 82 renal grafts. The Doppler resistance index in relation to the resistance index shows a highly statistical correlation by linear regression (R=0.813, p<0.0001). Primary graft function was recorded in 74 patients (90.24%) and it was highly statistically significant correlated with the resistance index measured by PM. Out of 8 patients with primary non-function, 6 patients recovered with normal graft function at one year.
The resistivity index recorded by the life-port machine is correlated with the vascular resistivity index measured by Doppler ultrasound and thus it may predicts the primary graft outcome.
随着移植器官的短缺日益严重，寻找增加供体器官库的方法仍然至关重要。灌注机（PM）已被证明可提高肾移植更快发挥功能、维持更长时间的可能性，从而为患者提供提高生活质量的机会。
本研究的目的是评估灌注机提供的阻力指数、术后通过多普勒超声测量的阻力指数与初始移植结果之间的关系。
在2012年1月至2012年12月期间，对82例连续接受脑死亡供体（BDD）肾移植并进行灌注机维护的临床数据进行横向研究分析。在移植前，我们记录了溶液温度、过滤率和灌注机提供的阻力指数。手术干预后，对每位患者进行标准随访。在术后第一天记录多普勒超声电阻指数（RI）。
在115例肾移植中，98例（85.21%）使用了BDD的移植物。82例肾移植物使用了灌注机。通过线性回归分析，多普勒阻力指数与阻力指数之间显示出高度统计学相关性（R=0.813，p<0.0001）。74例患者（90.24%）记录有原发性移植物功能，且与灌注机测量的阻力指数高度相关。在8例原发性无功能患者中，6例在一年时恢复了正常移植物功能。
生命端口机器记录的电阻指数与多普勒超声测量的血管电阻指数相关，因此它可能预测原发性移植物结果。
