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静脉输注利多卡因治疗化疗引起的周围神经病变。

Intravenous Lidocaine Infusion to Treat Chemotherapy-Induced Peripheral Neuropathy.

作者信息

Papapetrou Peter, Kumar Aashish J, Muppuri Rudram, Chakrabortty Shushovan

机构信息

From the Department of Anesthesiology, Detroit Medical Center, Wayne State University, Detroit, Michigan.

出版信息

A A Case Rep. 2015 Nov 1;5(9):154-5. doi: 10.1213/XAA.0000000000000197.

DOI:10.1213/XAA.0000000000000197
PMID:26528700
Abstract

Chemotherapy-induced peripheral neuropathy is a debilitating side effect of chemotherapy, which manifests as paresthesias, dysesthesias, and numbness in the hands and feet. Numerous chemoprotective agents and treatments have been used with limited success to treat chemotherapy-induced peripheral neuropathy. We report a case in which a patient presenting with chemotherapy-induced peripheral neuropathy received an IV lidocaine infusion over the course of 60 minutes with complete symptomatic pain relief for a prolonged period of 2 weeks.

摘要

化疗引起的周围神经病变是化疗的一种使人衰弱的副作用,表现为手足的感觉异常、感觉障碍和麻木。许多化学保护剂和治疗方法用于治疗化疗引起的周围神经病变,但效果有限。我们报告一例病例,一名患有化疗引起的周围神经病变的患者在60分钟内接受了静脉注射利多卡因,症状性疼痛完全缓解,且持续了长达2周的时间。

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