Banerjee Arghya, Santra Sourav Kumar, Mohanta Prakash Ranjan, Patel Bhisma K
Department of Chemistry, Indian Institute of Technology Guwahati , North Guwahati 781039, India.
Org Lett. 2015 Nov 20;17(22):5678-81. doi: 10.1021/acs.orglett.5b02967. Epub 2015 Nov 3.
Ruthenium(II) catalyzed oxidative C-H/O-H annulations have been demonstrated using two different directing arenes viz. 2-arylquinolinone and 2-arylbenzoxazinone with internal alkynes. Regiospecific annulations have been observed for both directing arenes via the assistance of weaker carbonyl oxygen in the presence of a stronger nitrogen-directing site. In this substrate-controlled convergent protocol the weaker directing group dictates the annulation path.
已证明钌（II）催化的氧化C-H/O-H环化反应可使用两种不同的导向芳烃，即2-芳基喹啉酮和2-芳基苯并恶嗪酮与内炔烃进行。在较强的氮导向位点存在的情况下，通过较弱的羰基氧的辅助，两种导向芳烃均观察到区域特异性环化反应。在这种底物控制的收敛反应中，较弱的导向基团决定了环化路径。
