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[胃肠道在新陈代谢中的作用:I. P. 拉先科夫观点的证实与进一步发展]

[The role of the gastrointestinal tract in metabolism: the confirmation and further development of the ideas of I. P. Razenkov].

作者信息

Shlygin G K

出版信息

Vestn Akad Med Nauk SSSR. 1989(1):69-80.

PMID:2652914
Abstract

According to the conception proposed by I. P. Razenkov, in addition to digestion proper, the gastro-intestinal tract is responsible for processes directly supporting metabolism. This conception has provided the basis for the modern concept of the circulation of a great amount of endogenous nutrients, proteins in particular, between blood and the digestive tract, which enriches and corrects the composition of exogenous proteins. Hepato-intestinal circulation of substances is a similar process too. Studies of active adaptations of the digestive glands to qualitative changes in nutrition have provided another evidence in its favor. There are several pathways to connect gastrointestinal tract with metabolism, according to the data accumulated up to now. In addition to the above-mentioned ones, they include gastro intestinal participation in hormonal control metabolism, excretory processes, biochemical activity of normal intestinal flora, etc. A rapidly progressing area of experimental and clinical research, dealing with the role of dietary fibres in nutrition is directly rooted in I. P. Razenkov's views and perfectly confirms their validity.

摘要

根据I. P. 拉泽恩科夫提出的概念,除了正常的消化功能外,胃肠道还负责直接支持新陈代谢的过程。这一概念为现代关于大量内源性营养物质,尤其是蛋白质在血液和消化道之间循环的概念奠定了基础,这种循环丰富并校正了外源性蛋白质的组成。物质的肝肠循环也是一个类似的过程。对消化腺对营养性质变化的主动适应性研究也为这一观点提供了另一证据。根据目前积累的数据,有几种途径将胃肠道与新陈代谢联系起来。除了上述途径外,还包括胃肠道参与激素对新陈代谢的控制、排泄过程、正常肠道菌群的生化活性等。一个迅速发展的实验和临床研究领域,即膳食纤维在营养中的作用,直接源于I. P. 拉泽恩科夫的观点,并完美地证实了其正确性。

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