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本文引用的文献

1
Interventional management of head and neck emergencies: carotid blowout.头颈部急症的介入治疗:颈动脉破裂
Semin Intervent Radiol. 2013 Sep;30(3):245-8. doi: 10.1055/s-0033-1353477.
2
Polytetrafluoroethylene-covered nitinol stent graft for treatment of carotid artery blowout syndrome in head and neck cancer patients.聚四氟乙烯覆膜镍钛合金支架移植物治疗头颈部癌症患者颈动脉破裂综合征。
Laryngoscope. 2013 Jul;123(7):1670-5. doi: 10.1002/lary.24006. Epub 2013 Mar 11.
3
Acute life-threatening hemorrhage in patients with head and neck cancer presenting with carotid blowout syndrome: follow-up results after initial hemostasis with covered-stent placement.头颈部癌伴颈动脉破裂综合征患者发生危及生命的急性大出血:初始采用覆膜支架置入进行止血后的随访结果。
AJNR Am J Neuroradiol. 2011 Apr;32(4):743-7. doi: 10.3174/ajnr.A2379. Epub 2011 Mar 24.
4
Covered stent treatment of carotid blowout syndrome.覆膜支架治疗颈动脉破裂综合征。
Semin Intervent Radiol. 2007 Mar;24(1):47-52. doi: 10.1055/s-2007-971189.
5
Update on endovascular management of the carotid blowout syndrome.
Neuroimaging Clin N Am. 2009 May;19(2):271-81, Table of Contents. doi: 10.1016/j.nic.2009.01.001.
6
Patients with head and neck cancers and associated postirradiated carotid blowout syndrome: endovascular therapeutic methods and outcomes.头颈部癌症患者及相关放疗后颈动脉破裂综合征:血管内治疗方法及结果
J Vasc Surg. 2008 May;47(5):936-45. doi: 10.1016/j.jvs.2007.12.030. Epub 2008 Mar 6.
7
Stent-grafts in the treatment of emergent or urgent carotid artery disease: review of 25 cases.覆膜支架治疗急性或亚急性颈动脉疾病:25例病例回顾
J Vasc Interv Radiol. 2008 Jan;19(1):31-41. doi: 10.1016/j.jvir.2007.08.024.
8
Placement of covered stents for carotid blowout in patients with head and neck cancer: follow-up results after rescue treatments.头颈部癌患者颈动脉破裂置入覆膜支架:挽救治疗后的随访结果
AJNR Am J Neuroradiol. 2007 Sep;28(8):1594-8. doi: 10.3174/ajnr.A0589.
9
Carotid blowout syndrome in patients with head-and-neck cancers: reconstructive management by self-expandable stent-grafts.头颈部癌症患者的颈动脉破裂综合征:采用自膨式覆膜支架的重建治疗
AJNR Am J Neuroradiol. 2007 Jan;28(1):181-8.
10
Brain abscess formation: a delayed complication of carotid blowout syndrome treated by self-expandable stent-graft.脑脓肿形成:一种经自膨式支架型人工血管治疗的颈动脉破裂综合征的迟发性并发症。
AJNR Am J Neuroradiol. 2006 Aug;27(7):1543-5.

头颈部癌症患者颈动脉破裂综合征覆膜支架治疗的随访

Follow-up for covered stent treatment of carotid blow-out syndrome in patients with head and neck cancer.

作者信息

Wu Chia-Jen, Lin Wei-Chen, Hsu Jui-Sheng, Han I-Ting, Hsieh Tsyh-Jyi, Liu Gin-Chung, Chiang I-Chan

机构信息

1 Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.

2 Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

出版信息

Br J Radiol. 2016;89(1058):20150136. doi: 10.1259/bjr.20150136. Epub 2015 Nov 3.

DOI:10.1259/bjr.20150136
PMID:26529227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4985188/
Abstract

OBJECTIVE

Carotid blow-out syndrome (CBS) is a life-threatening complication of head and neck cancer (HNC). One of the various methods used for emergency management of CBS is covered stent placement (CSP). Our initial experience in CSP is evaluated and compared with reports in the literature.

METHODS

This study analysed 17 patients with HNC who had received CSP for CBS at Kaohsiung Medical University Chung-Ho Memorial Hospital from May 2005 to December 2013. The medical records and images for these patients were retrospectively reviewed to evaluate the causes of CBS, treatment success rates and complications.

RESULTS

The initial angiography success rate was 100%. Procedural or periprocedural complications were noted in two (12%) cases, both suffering from cerebral vascular accident (CVA). Short-term complications were noted in eight (47%) cases, including four rebleeding cases and four CVA cases. Medium- to long-term complications were noted in nine cases, which included two asymptomatic in-stent thrombosis cases, one symptomatic CVA case, two abscess formation cases and four rebleeding cases. Overall, eight (47%) cases of rebleeding occurred during follow-up. Three of the eight cases were fatal, accounting for 27% of the all-cause mortality.

CONCLUSION

Although CSP is considered effective for achieving haemostasis in patients with HNC with CBS, the medium- to long-term outcomes are unfavourable owing to high risks of rebleeding, CVA and other complications. Therefore, CSP should be considered a temporary life-saving technique rather than a definitive treatment.

ADVANCES IN KNOWLEDGE

Analysis of the relatively large series of patients with HNC in this study suggests that CSP is a useful temporary treatment for CBS.

摘要

目的

颈动脉破裂综合征(CBS)是头颈部癌(HNC)的一种危及生命的并发症。用于CBS紧急处理的多种方法之一是覆膜支架置入术(CSP)。我们对CSP的初步经验进行评估,并与文献报道进行比较。

方法

本研究分析了2005年5月至2013年12月在高雄医学大学中和纪念医院接受CSP治疗CBS的17例HNC患者。对这些患者的病历和影像进行回顾性分析,以评估CBS的病因、治疗成功率及并发症。

结果

初始血管造影成功率为100%。2例(12%)出现术中或围手术期并发症,均发生脑血管意外(CVA)。8例(47%)出现短期并发症,包括4例再出血和4例CVA。9例出现中长期并发症,包括2例无症状支架内血栓形成、1例有症状CVA、2例脓肿形成和4例再出血。总体而言,随访期间有8例(47%)发生再出血。8例中有3例死亡,占全因死亡率的27%。

结论

尽管CSP被认为对HNC合并CBS患者实现止血有效,但由于再出血、CVA及其他并发症风险高,中长期预后不佳。因此,CSP应被视为一种临时的救命技术而非确定性治疗。

知识进展

本研究对相对大量的HNC患者进行分析表明,CSP是CBS的一种有用的临时治疗方法。