Wu Chia-Jen, Lin Wei-Chen, Hsu Jui-Sheng, Han I-Ting, Hsieh Tsyh-Jyi, Liu Gin-Chung, Chiang I-Chan
1 Department of Medical Imaging, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
2 Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Br J Radiol. 2016;89(1058):20150136. doi: 10.1259/bjr.20150136. Epub 2015 Nov 3.
Carotid blow-out syndrome (CBS) is a life-threatening complication of head and neck cancer (HNC). One of the various methods used for emergency management of CBS is covered stent placement (CSP). Our initial experience in CSP is evaluated and compared with reports in the literature.
This study analysed 17 patients with HNC who had received CSP for CBS at Kaohsiung Medical University Chung-Ho Memorial Hospital from May 2005 to December 2013. The medical records and images for these patients were retrospectively reviewed to evaluate the causes of CBS, treatment success rates and complications.
The initial angiography success rate was 100%. Procedural or periprocedural complications were noted in two (12%) cases, both suffering from cerebral vascular accident (CVA). Short-term complications were noted in eight (47%) cases, including four rebleeding cases and four CVA cases. Medium- to long-term complications were noted in nine cases, which included two asymptomatic in-stent thrombosis cases, one symptomatic CVA case, two abscess formation cases and four rebleeding cases. Overall, eight (47%) cases of rebleeding occurred during follow-up. Three of the eight cases were fatal, accounting for 27% of the all-cause mortality.
Although CSP is considered effective for achieving haemostasis in patients with HNC with CBS, the medium- to long-term outcomes are unfavourable owing to high risks of rebleeding, CVA and other complications. Therefore, CSP should be considered a temporary life-saving technique rather than a definitive treatment.
Analysis of the relatively large series of patients with HNC in this study suggests that CSP is a useful temporary treatment for CBS.
颈动脉破裂综合征(CBS)是头颈部癌(HNC)的一种危及生命的并发症。用于CBS紧急处理的多种方法之一是覆膜支架置入术(CSP)。我们对CSP的初步经验进行评估,并与文献报道进行比较。
本研究分析了2005年5月至2013年12月在高雄医学大学中和纪念医院接受CSP治疗CBS的17例HNC患者。对这些患者的病历和影像进行回顾性分析,以评估CBS的病因、治疗成功率及并发症。
初始血管造影成功率为100%。2例(12%)出现术中或围手术期并发症,均发生脑血管意外(CVA)。8例(47%)出现短期并发症,包括4例再出血和4例CVA。9例出现中长期并发症,包括2例无症状支架内血栓形成、1例有症状CVA、2例脓肿形成和4例再出血。总体而言,随访期间有8例(47%)发生再出血。8例中有3例死亡,占全因死亡率的27%。
尽管CSP被认为对HNC合并CBS患者实现止血有效,但由于再出血、CVA及其他并发症风险高,中长期预后不佳。因此,CSP应被视为一种临时的救命技术而非确定性治疗。
本研究对相对大量的HNC患者进行分析表明,CSP是CBS的一种有用的临时治疗方法。