Samardzija Gordana, Djuricic Slavisa M, Baljosevic Ivan, Calonje Eduardo
1 Department of Clinical Pathology, Mother and Child Health Care Institute of Serbia Dr Vukan Cupic, Belgrade, Serbia.
2 Banjaluka University School of Medicine, Banjaluka, Bosnia and Herzegovina.
Pediatr Dev Pathol. 2016 May-Jun;19(3):249-53. doi: 10.2350/14-09-1547-CR.1. Epub 2015 Nov 3.
There are only 8 published cases of symplastic hemangioma (SH), a relatively recently described, distinct benign entity characterized by pleomorphic vascular smooth muscle and interstitial cells in a pre-existing, long-standing vascular lesion. Seven of these cases were of SH in cutaneous locations, and 1 case was described in the mediastinum. We report the case of the 12-year-old girl with a nasopharyngeal tumor mass with prominent symplastic changes arising in the background of a combined capillary arteriovenous malformation. After critical analysis of all published cases of SH, it is clear that these lesions commonly represent capillary arteriovenous malformations (CAVM) with ancient/symplastic changes according to current terminology proposed in the classification required by the International Society for the Study of Vascular Anomalies (ISSVA). This is the first such lesion reported in a mucosal location and presenting in the pediatric age group. CAVM with ancient/symplastic change follows a benign clinical course, but it can simulate a malignant vascular tumor.
共生性血管瘤（SH）仅有8例已发表的病例报道，这是一种相对较新描述的独特良性病变，其特征是在先前存在的长期血管病变中存在多形性血管平滑肌和间质细胞。其中7例为皮肤部位的SH，1例发生于纵隔。我们报告了一名12岁女孩的病例，该女孩患有鼻咽部肿瘤块，在合并的毛细血管动静脉畸形背景下出现明显的共生性改变。在对所有已发表的SH病例进行批判性分析后，很明显，根据国际血管畸形研究学会（ISSVA）分类要求中提出的当前术语，这些病变通常代表具有陈旧性/共生性改变的毛细血管动静脉畸形（CAVM）。这是首次报道在黏膜部位出现且发生于儿童年龄组的此类病变。伴有陈旧性/共生性改变的CAVM遵循良性临床病程，但可类似恶性血管肿瘤。
