Perea J, Rodríguez Luna J M, Fernández A, Escudero Barrilero A
Actas Urol Esp. 1989 Jan-Feb;13(1):24-7.
Penile carcinoma is a rather infrequent neoplasia with an approximate annual rate of 1 to 2 cases per 100,000 inhabitants. In Spain, its presentation is rare, corresponding to 10.42% of all tumors and 0.7% of all malignant tumors of the male. In this report, the casuistic of our Department between the years 1978 and 1987 is presented. Ten patients diagnosed of penile carcinoma were treated, representing 0.1% of all the urological tumors seen during that period. Special emphasis has been placed on the need to perform national multicenter studies, due to the rare finding of such pathology. From an etiopathogenic perspective, chronic inflammation due to smegma accumulation and the presence of a prepuce seem necessary for the development of this pathology. The role of oncogenic viruses still remains to be cleared. After treatment, which was mainly surgical, a global survival rate of 60% was obtained with a follow-up period ranging from 1 month to 7 years. After pointing out several anatomical considerations relating to the lymph drainage of the penis, the different therapeutic alternatives (surgery, radiotherapy, chemotherapy) in the treatment of penile carcinoma were discussed.
阴茎癌是一种较为罕见的肿瘤，年发病率约为每10万居民1至2例。在西班牙，其发病率很低，占所有肿瘤的10.42%，占男性所有恶性肿瘤的0.7%。在本报告中，介绍了我们科室1978年至1987年间的病例情况。10例被诊断为阴茎癌的患者接受了治疗，占该时期所有泌尿系统肿瘤的0.1%。由于这种病理情况罕见，因此特别强调有必要开展全国性多中心研究。从病因学角度来看，包皮垢积聚导致的慢性炎症以及包皮的存在似乎是这种病理发展的必要条件。致癌病毒的作用仍有待明确。治疗主要采用手术方式，随访期为1个月至7年，总体生存率为60%。在指出了一些与阴茎淋巴引流相关的解剖学因素后，讨论了阴茎癌治疗中的不同治疗选择（手术、放疗、化疗）。
