Katchen M, Gronseth G S
Neuropsychiatry Branch, USAF School of Aerospace Medicine, Brooks Air Force Base, Texas.
Aviat Space Environ Med. 1989 Mar;60(3):263-7.
From 1958 to 1986, 27 crewmembers with suspected sleep disorders were referred to the USAF School of Aerospace Medicine. The presenting complaint in most cases was excessive daytime sleepiness (EDS). Prior to 1984, evaluations included neurologic and psychiatric testing, screening laboratory studies, and awake and asleep electroencephalography. Polysomnography and sleep latency studies were included after 1984. In the majority of cases, the etiology of the complaint could not be determined. The prevalence of EDS is estimated to be between 0.3% and 4.0% of the adult population. Major causes cited in the world literature include the sleep apnea syndromes, narcolepsy, parasomnias interrupting sleep, hypersomnia secondary to systemic or affective disorders, and essential hypersomnia. Current sleep lab techniques and human leukocyte antigen (HLA) typing are reported to make the diagnosis in up to 90% of sleep disorders. Evaluation of EDS should begin with a history emphasizing sleep habits, work schedules, daytime naps, and presence of vegetative signs. A sleep diary will allow a more accurate estimate of the quantity of nocturnal sleep. This diary may reveal poor sleep hygiene or insomnia. Polysomnography and/or multiple sleep latency determination can then be used to diagnose sleep apnea, parasomnias, and narcolepsy.
1958年至1986年期间,27名疑似患有睡眠障碍的机组人员被转至美国空军航空航天医学院。大多数病例的主要症状是日间过度嗜睡(EDS)。1984年之前的评估包括神经学和精神病学检查、筛选实验室研究以及清醒和睡眠状态下的脑电图检查。1984年之后增加了多导睡眠图和睡眠潜伏期研究。在大多数病例中,无法确定症状的病因。据估计,成人中EDS的患病率在0.3%至4.0%之间。世界文献中提到的主要病因包括睡眠呼吸暂停综合征、发作性睡病、干扰睡眠的异态睡眠、继发于全身性或情感性疾病的睡眠过多以及原发性睡眠过多。据报道,目前的睡眠实验室技术和人类白细胞抗原(HLA)分型能够诊断高达90%的睡眠障碍。对EDS的评估应从详细询问睡眠习惯、工作时间表、日间小睡以及是否存在自主神经症状开始。睡眠日记有助于更准确地估计夜间睡眠量。这本日记可能会揭示不良的睡眠卫生习惯或失眠情况。然后可以使用多导睡眠图和/或多次睡眠潜伏期测定来诊断睡眠呼吸暂停、异态睡眠和发作性睡病。