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The cellular basis of T-cell memory.

作者信息

Cerottini J C, MacDonald H R

机构信息

Ludwig Institute for Cancer Research, Lausanne Branch, Epalinges, Switzerland.

出版信息

Annu Rev Immunol. 1989;7:77-89. doi: 10.1146/annurev.iy.07.040189.000453.

DOI:10.1146/annurev.iy.07.040189.000453
PMID:2653379
Abstract
摘要

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The cellular basis of T-cell memory.T细胞记忆的细胞基础。
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[Cellular basis of immunologic recognition. I. Relationship and cooperative interaction between subpopulations of T- and B-lymphocytes during primary immunologic recognition].[免疫识别的细胞基础。I. 初次免疫识别过程中T淋巴细胞和B淋巴细胞亚群之间的关系及协同相互作用]
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Regulatory T cell memory.调节性T细胞记忆
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STAT4 and T-bet are required for the plasticity of IFN-γ expression across Th2 ontogeny and influence changes in Ifng promoter DNA methylation.STAT4 和 T-bet 是 IFN-γ 表达在 Th2 发生过程中可塑性所必需的,并且影响 Ifng 启动子 DNA 甲基化的变化。
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Rapid default transition of CD4 T cell effectors to functional memory cells.CD4 T细胞效应器迅速向功能性记忆细胞转变。
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Protective effect of DNA immunization against mycobacterial infection is associated with the early emergence of interferon-gamma (IFN-gamma)-secreting lymphocytes.DNA免疫对分枝杆菌感染的保护作用与早期出现分泌γ-干扰素(IFN-γ)的淋巴细胞有关。
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A single peripheral CD8+ T cell can give rise to progeny expressing type 1 and/or type 2 cytokine genes and can retain its multipotentiality through many cell divisions.单个外周CD8 + T细胞可产生表达1型和/或2型细胞因子基因的后代,并可通过多次细胞分裂保持其多能性。
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Distinct costimulatory molecules are required for the induction of effector and memory cytotoxic T lymphocytes.诱导效应性和记忆性细胞毒性T淋巴细胞需要不同的共刺激分子。
J Exp Med. 1997 Jan 20;185(2):251-62. doi: 10.1084/jem.185.2.251.
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Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization.黏膜免疫而非全身免疫后黏膜组织中存在长寿细胞毒性T淋巴细胞记忆。
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