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引用本文的文献

1
Response to Physiologically Based Pharmacokinetic Model for Prediction of Leflunomide and Teriflunomide-Should Consideration Be Given to Cannalicular Efflux Transporters?基于生理学的药代动力学模型对来氟米特和特立氟胺预测的反应——是否应考虑小管外排转运体？
CPT Pharmacometrics Syst Pharmacol. 2015 Oct;4(10):564. doi: 10.1002/psp4.12036. Epub 2015 Oct 9.

本文引用的文献

1
Semiphysiologically Based Pharmacokinetic Model of Leflunomide Disposition in Rheumatoid Arthritis Patients.类风湿关节炎患者中来氟米特处置的半生理药代动力学模型。
CPT Pharmacometrics Syst Pharmacol. 2015 Jun;4(6):362-71. doi: 10.1002/psp4.46. Epub 2015 Jun 15.
2
Leflunomide and its metabolite A771726 are high affinity substrates of BCRP: implications for drug resistance.来氟米特及其代谢产物A771726是乳腺癌耐药蛋白（BCRP）的高亲和力底物：对耐药性的影响。
Ann Rheum Dis. 2009 Jul;68(7):1201-7. doi: 10.1136/ard.2007.086264. Epub 2008 Apr 8.
3
Protective effects of hepatocellular canalicular conjugate export pump (Mrp2) on sodium arsenite-induced hepatic dysfunction in rats.肝细胞胆小管共轭转运泵（Mrp2）对亚砷酸钠诱导的大鼠肝功能障碍的保护作用。
Exp Toxicol Pathol. 2007 Aug;58(6):447-53. doi: 10.1016/j.etp.2007.02.001. Epub 2007 Apr 30.
4
Down-regulation of hepatic transporters for BSP in rats with indomethacin-induced intestinal injury.吲哚美辛诱导的大鼠肠道损伤中肝脏BSP转运体的下调
Biol Pharm Bull. 2007 Mar;30(3):556-61. doi: 10.1248/bpb.30.556.
5
Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene.对乙酰氨基酚在Mrp3基因敲除小鼠体内的处置改变。
Hepatology. 2005 Nov;42(5):1091-8. doi: 10.1002/hep.20898.

Physiologically Based Pharmacokinetic Model for Prediction of Leflunomide and Teriflunomide: Should Consideration Be Given to Cannalicular Efflux Transporters?

作者信息

Srinivas N R

机构信息

Suramus Bio, J.P. Nagar I Phase Bangalore, Karnataka, India.

出版信息

CPT Pharmacometrics Syst Pharmacol. 2015 Oct;4(10):563. doi: 10.1002/psp4.12033. Epub 2015 Oct 9.

DOI:10.1002/psp4.12033
PMID:26535155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4625859/
Abstract
摘要