• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一例因夹竹桃中毒导致的莫氏Ⅱ型房室传导阻滞,用地高辛特异性Fab抗体片段成功治疗。

A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments.

作者信息

Tatlısu Mustafa Adem, Çekirdekçi Elif İjlal, Akyüz Şükrü, Nurkalem Zekeriya

机构信息

Department of Cardiology, Sivas Numune State Hospital, Sivas, Turkey.

Department of Cardiology, Corlu State Hospital, Tekirdag, Turkey.

出版信息

Turk Kardiyol Dern Ars. 2015 Oct;43(7):648-50. doi: 10.5543/tkda.2015.65848.

DOI:10.5543/tkda.2015.65848
PMID:26536992
Abstract

Nerium oleander is a popular ornamental plant grown in many tropical and subtropical countries and in the Mediterranean region. It is dangerous because it has been shown to contain several types of cardiac glycosides, and hence can cause cardiac arrhythmias resembling digoxin in their toxicologic manifestations. We report a patient presenting to our hospital with Mobitz type II atrioventricular block after drinking herbal tea prepared from oleander leaves. Three hours after admission, a 200-mg empiric dose of digoxin-specific Fab antibody fragments was administered intravenously over 30 minutes. A 12-lead electrocardiogram (ECG) revealed sinus rhythm at the end of infusion. After 72 hours, the patient was discharged without any symptoms.

摘要

夹竹桃是一种常见的观赏植物,生长于许多热带和亚热带国家以及地中海地区。它很危险,因为已证明其含有多种类型的强心苷,因此在毒理学表现上可导致类似地高辛的心律失常。我们报告一名患者,饮用用夹竹桃叶泡制的草药茶后,以莫氏Ⅱ型房室传导阻滞就诊于我院。入院3小时后,静脉注射200毫克经验剂量的地高辛特异性Fab抗体片段,持续30分钟。输注结束时,12导联心电图(ECG)显示窦性心律。72小时后,患者无症状出院。

相似文献

1
A case of Mobitz type II atrioventricular block due to Nerium oleander poisoning successfully managed with digoxin-specific Fab antibody fragments.一例因夹竹桃中毒导致的莫氏Ⅱ型房室传导阻滞,用地高辛特异性Fab抗体片段成功治疗。
Turk Kardiyol Dern Ars. 2015 Oct;43(7):648-50. doi: 10.5543/tkda.2015.65848.
2
Beneficial effect of digoxin-specific Fab antibody fragments in oleander intoxication.地高辛特异性Fab抗体片段在夹竹桃中毒中的有益作用。
Arch Intern Med. 1995 Oct 23;155(19):2121-5.
3
Management of yellow oleander poisoning.黄夹竹桃中毒的处理
Clin Toxicol (Phila). 2009 Mar;47(3):206-12. doi: 10.1080/15563650902824001.
4
A suicide attempt by ingestion of oleander leaves and treatment with digoxin-specific Fab antibody fragments.摄入夹竹桃叶和使用洋地黄特异性 Fab 抗体片段进行治疗的自杀企图。
Arh Hig Rada Toksikol. 2023 Dec 29;74(4):292-295. doi: 10.2478/aiht-2023-74-3752. eCollection 2022.
5
Transitory complete atrioventricular block associated to ingestion of Nerium oleander.与夹竹桃摄入相关的暂时性完全性房室传导阻滞
Rev Assoc Med Bras (1992). 1995 Jan-Feb;41(1):60-2.
6
A review of the natural history, toxinology, diagnosis and clinical management of Nerium oleander (common oleander) and Thevetia peruviana (yellow oleander) poisoning.夹竹桃和黄花夹竹桃中毒的自然史、毒素学、诊断和临床处理综述。
Toxicon. 2010 Sep 1;56(3):273-81. doi: 10.1016/j.toxicon.2010.03.026. Epub 2010 May 8.
7
Complete atrioventricular block after self-ingestion of Nerium oleander for relief of hemorrhoidal complaints.因自行服用夹竹桃以缓解痔疮症状后出现完全性房室传导阻滞。
Turk Kardiyol Dern Ars. 2012 Mar;40(2):168-70. doi: 10.5543/tkda.2012.01703.
8
Electrocardiographic changes during inhalational oleander toxicity.吸入夹竹桃中毒时的心电图变化。
J Electrocardiol. 2011 Jul-Aug;44(4):470-2. doi: 10.1016/j.jelectrocard.2010.12.002. Epub 2011 Mar 12.
9
Oleander poisoning: treatment with digoxin-specific Fab antibody fragments.夹竹桃中毒:用地高辛特异性Fab抗体片段治疗。
Ann Emerg Med. 1988 Jul;17(7):732-5. doi: 10.1016/s0196-0644(88)80625-5.
10
Oleander tea: herbal draught of death.夹竹桃茶:致命的草药饮品。
Ann Emerg Med. 1985 Apr;14(4):350-3. doi: 10.1016/s0196-0644(85)80103-7.

引用本文的文献

1
Antidote use for cardiac arrest or hemodynamic instability due to cardiac glycoside poisoning: A narrative review.用于治疗洋地黄中毒所致心脏骤停或血流动力学不稳定的解毒剂:一项叙述性综述。
Resusc Plus. 2024 Jun 21;19:100690. doi: 10.1016/j.resplu.2024.100690. eCollection 2024 Sep.
2
Comprehensive review of cardiovascular toxicity of drugs and related agents.药物和相关制剂的心血管毒性的综合评价
Med Res Rev. 2018 Jul;38(4):1332-1403. doi: 10.1002/med.21476. Epub 2018 Jan 5.