Jínek T, Adamčík L, Duda M, Škrovina M
Rozhl Chir. 2015 Sep;94(9):362-6.
Gastric stump cancer accounts for 14% of all gastric carcinomas. Originally this term included patients who previously underwent surgery due to peptic ulcer disease but today gastric stump cancer also includes patients diagnosed some time after primary gastric resection due to gastric cancer. The incidence is increasing. Gastric stump cancer is associated with poor prognosis and its reported resecability is around 40%.
We retrospectively analyzed the data of 7 patients with a preoperatively histologically confirmed stump cancer who had been operated at the Department of Surgery at Nový Jičín Hospital during 2006-2014.
We operated 5 men and 2 women with the median age of 70 years (5580). The primary surgical resection in all our patients was BII gastric resection due to peptic ulcer disease, and GSC had evolved within a median of 38 years (3246) after primary intervention. None of the patients had been regularly screened by endoscopy following primary surgery. We performed five curative resections (four total gastrectomies, one subtotal gastrectomy). Our resecability rate was 71%. In two cases, only explorative laparotomy was performed due to generalisation of the malignancy. Two patients from the resected group died after 30 and 34 months due to progression of their disease; the other three patients are still alive after 17, 19 and 88 months.
Gastric stump cancer is a malignancy often diagnosed in its late stages. Regural endoscopic screening after primary gastric resection for benign disease can lead to diagnosis at an earlier stage, thereby improving the resection rate and overall survival. This also applies to long-term follow-up of patients with primary subtotal gastrectomy for cancer. Lymphatic metastasizing of the carcinoma can often be different due to the previous surgical intervention and altered anatomy. This must be taken into account during operations.
残胃癌占所有胃癌的14%。最初,这个术语包括那些因消化性溃疡疾病先前接受过手术的患者,但如今残胃癌还包括因胃癌接受初次胃切除术后一段时间被诊断出的患者。其发病率正在上升。残胃癌预后较差,据报道其可切除率约为40%。
我们回顾性分析了2006年至2014年期间在新伊钦医院外科接受手术的7例术前经组织学确诊为残胃癌患者的数据。
我们为5名男性和2名女性实施了手术,中位年龄为70岁(55 - 80岁)。我们所有患者的初次手术切除均为因消化性溃疡疾病行毕Ⅱ式胃切除术,残胃癌在初次干预后中位38年(32 - 46年)内发生。初次手术后没有患者接受过定期内镜筛查。我们进行了5例根治性切除术(4例全胃切除术,1例次全胃切除术)。我们的可切除率为71%。在2例患者中,由于恶性肿瘤扩散仅进行了探查性剖腹术。切除组的2例患者分别在30个月和34个月后因疾病进展死亡;其他3例患者在17、19和88个月后仍存活。
残胃癌是一种常被诊断为晚期的恶性肿瘤。对良性疾病进行初次胃切除术后定期内镜筛查可在更早阶段实现诊断,从而提高切除率和总体生存率。这也适用于因癌症接受初次次全胃切除术患者的长期随访。由于先前的手术干预和解剖结构改变,癌的淋巴转移情况通常可能不同。手术期间必须考虑到这一点。