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减重手术后的继发性甲状旁腺功能亢进:治疗应使用碳酸钙还是枸橼酸钙?

SECONDARY HYPERPARATHYROIDISM AFTER BARIATRIC SURGERY: TREATMENT IS WITH CALCIUM CARBONATE OR CALCIUM CITRATE?

作者信息

Baretta Giorgio Alfredo Pedroso, Cambi Maria Paula Carlini, Rodrigues Arieli Luz, Mendes Silvana Aparecida

机构信息

Vita Batel Hospital, Curitiba, PR, Brazil.

出版信息

Arq Bras Cir Dig. 2015;28 Suppl 1(Suppl 1):43-5. doi: 10.1590/S0102-6720201500S100013.

Abstract

BACKGROUND

Bariatric surgery, especially Roux-en-Y gastric bypass, can cause serious nutritional complications arising from poor absorption of essential nutrients. Secondary hyperparathyroidism is one such complications that leads to increased parathyroid hormone levels due to a decrease in calcium and vitamin D, which may compromise bone health.

AIM

To compare calcium carbonate and calcium citrate in the treatment of secondary hyperparathyroidism.

METHOD

Patients were selected on the basis of their abnormal biochemical test and treatment was randomly done with citrate or calcium carbonate.

RESULTS

After 60 days of supplementation, biochemical tests were repeated, showing improvement in both groups.

CONCLUSION

Supplementation with calcium (citrate or carbonate) and vitamin D is recommended after surgery for prevention of secondary hyperparathyroidism.

摘要

背景

减肥手术,尤其是 Roux-en-Y 胃旁路手术,可因必需营养素吸收不良而导致严重的营养并发症。继发性甲状旁腺功能亢进就是其中一种并发症,由于钙和维生素 D 减少,导致甲状旁腺激素水平升高,这可能损害骨骼健康。

目的

比较碳酸钙和枸橼酸钙治疗继发性甲状旁腺功能亢进的效果。

方法

根据生化检查异常选择患者,并随机给予枸橼酸钙或碳酸钙进行治疗。

结果

补充 60 天后,重复进行生化检查,两组均有改善。

结论

建议术后补充钙(枸橼酸钙或碳酸钙)和维生素 D 以预防继发性甲状旁腺功能亢进。

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