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利用眼前节光学相干断层扫描技术对一名婴儿后圆锥角膜的新特征描述:病例报告

A novel characterization of posterior keratoconus using anterior segment optical coherence tomography in an infant: a case report.

作者信息

Garg Nisha, Chang Ta C, Reiser Bibiana Jin, Cavuoto Kara M

机构信息

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 900 NW 17th St, Miami, FL, 33136, USA.

Children's Hospital Los Angeles, 4650 Sunset Blvd., Los Angeles, CA, 90027, USA.

出版信息

BMC Ophthalmol. 2015 Nov 4;15:158. doi: 10.1186/s12886-015-0139-3.

DOI:10.1186/s12886-015-0139-3
PMID:26537455
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4634598/
Abstract

BACKGROUND

Posterior keratoconus is a rare cause of a corneal opacity in an infant. It is characterized by thinning of the posterior cornea without ectasia of the anterior cornea. Imaging of this condition with anterior segment optical coherence tomography (AS-OCT) has not been reported in the literature.

CASE PRESENTATION

A six week old African-American male presented with a congenital corneal opacity of the right eye. He underwent an examination under anesthesia in which photography and AS-OCT were performed. AS-OCT confirmed the diagnosis of posterior keratoconus. The patient subsequently underwent an optical iridectomy for visual development.

CONCLUSION

AS-OCT is a useful tool in cases when a child presents with a corneal opacity of unknown or unclear etiology. In our patient, AS-OCT showed the classic description of central corneal thinning seen in this condition. Additionally, it revealed an associated detached Descemet membrane, a feature which has not been previously described in posterior keratoconus.

摘要

背景

后圆锥角膜是婴儿角膜混浊的罕见病因。其特征是后角膜变薄而无前角膜扩张。文献中尚未报道使用眼前节光学相干断层扫描(AS-OCT)对该病症进行成像。

病例介绍

一名六周大的非裔美国男性因右眼先天性角膜混浊前来就诊。他在麻醉下接受了检查,期间进行了摄影和AS-OCT检查。AS-OCT确诊为后圆锥角膜。该患者随后接受了光学虹膜切除术以促进视觉发育。

结论

当儿童出现病因不明或不清楚的角膜混浊时,AS-OCT是一种有用的工具。在我们的患者中,AS-OCT显示了这种病症中典型的中央角膜变薄情况。此外,它还揭示了相关的后弹力层脱离,这是后圆锥角膜以前未曾描述过的一个特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32ef/4634598/785d33ea5b48/12886_2015_139_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32ef/4634598/44a45f02b496/12886_2015_139_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32ef/4634598/785d33ea5b48/12886_2015_139_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32ef/4634598/44a45f02b496/12886_2015_139_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32ef/4634598/785d33ea5b48/12886_2015_139_Fig2_HTML.jpg

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引用本文的文献

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A case of unilateral circumscribed posterior keratoconus evaluated by three different imaging tools: optical coherence tomography, videokeratography, and Scheimpflug corneal tomography.一例通过三种不同成像工具评估的单侧局限性后圆锥角膜:光学相干断层扫描、角膜地形图和Scheimpflug角膜断层扫描。
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