喉及下咽非上皮性肿瘤——12年经验
Non-epithelial neoplasms of the larynx and hypopharynx - 12 - years of experience.
作者信息
Rzepakowska Anna, Osuch-Wójcikiewicz Ewa, Bruzgielewicz Antoni, Niemczyk Kazimierz
机构信息
Otolaryngology Department of Warsaw Medical University, Warsaw, Poland.
出版信息
Otolaryngol Pol. 2015;69(5):9-15. doi: 10.5604/00306657.1170420.
OBJECTIVE
The non-epithelial neoplasms of larynx and hypopharynx are of rare incidence but may originate from various histological tissues. These effect in the difficulty of final diagnosis and often delay the proper treatment.
MATERIAL AND METHODS
There was performed retrospective analysis of patients with histopathologicaly confirmed non-epithelial neoplasms of larynx or hypopharynx between 2001 and 2013, that included the evaluation of epidemiology, diagnostic methods and treatment.
RESULTS
Non-epithelial neoplasms of larynx and hypopharynx were established in 18 patients (9 women, 9 men), mean age - 60,3 years. The malignant neoplasms were diagnosed in 10 patients and benign - in 8. The soft tissue neoplasms were the most common - 8 patients. There were also 4 lymphomas, 4 chondrosarcomas, 1 paraganglioma and 1 malignant melanoma. Tumors manifested clinically as covered by unchanged mucosa. Characteristic features were observed on computed tomography for certain cases of these neoplasms. The results of the tumor biopsy were in most of the cases not diagnostic. Intralaryngeal microsurgery was applied in benign neoplasms, chemiotherapy - for lymphomas and total laryngectomy for chondrosarcomas and malignant melanoma.
目的
喉和下咽的非上皮性肿瘤发病率很低，但可能起源于多种组织学类型。这给最终诊断带来困难，并常常延误恰当治疗。
材料与方法
对2001年至2013年间组织病理学确诊的喉或下咽非上皮性肿瘤患者进行回顾性分析，内容包括流行病学、诊断方法及治疗评估。
结果
18例患者（9例女性，9例男性）确诊为喉和下咽非上皮性肿瘤，平均年龄60.3岁。10例诊断为恶性肿瘤，8例为良性肿瘤。软组织肿瘤最为常见，共8例。此外还有4例淋巴瘤、4例软骨肉瘤、1例副神经节瘤和1例恶性黑色素瘤。肿瘤临床表现为黏膜未受侵犯。部分病例在计算机断层扫描上有特征性表现。多数情况下肿瘤活检结果无法确诊。良性肿瘤采用喉内显微手术治疗，淋巴瘤采用化疗，软骨肉瘤和恶性黑色素瘤采用全喉切除术。
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